Firmness without filler.
Book your Hyperdilute Radiesse consultation at Dr Hans Clinics, London.
Hyperdilute Radiesse - biostimulator
Hyperdilute Radiesse London - Collagen Stimulation and Tissue Firming
Hyperdilute Radiesse® (calcium hydroxylapatite, Merz Aesthetics) is a regenerative injectable that improves skin elasticity and firmness through controlled collagen induction.
When diluted and placed in the superficial dermis, it remodels tissue gradually – improving tone and structure without creating bulk.
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MECHANISM OF ACTION
● Contains CaHA microspheres suspended in gel carrier.
● When diluted, microspheres act as a scaffold for fibroblast activation, leading to new type I & III collagen and elastin formation.
● The carrier gel is absorbed, leaving firmer, naturally remodelled skin.
Onset : 4 – 6 weeks Peak : 3 months Duration : 12 – 18 months
● When diluted, microspheres act as a scaffold for fibroblast activation, leading to new type I & III collagen and elastin formation.
● The carrier gel is absorbed, leaving firmer, naturally remodelled skin.
Onset : 4 – 6 weeks Peak : 3 months Duration : 12 – 18 months
WHY PATIENTS CHOOSE DR HANS CLINICS
● Doctor-led protocols using evidence-based dilution ratios.
● CE-certified Merz product handled under aseptic conditions.
● Ideal for face, neck, decolletage, arms, or knees.
● Focus on measurable collagen change, not over-filling.
● CE-certified Merz product handled under aseptic conditions.
● Ideal for face, neck, decolletage, arms, or knees.
● Focus on measurable collagen change, not over-filling.
EVIDENCE & SAFETY
● Peer-reviewed research shows calcium hydroxylapatite significantly increases dermal thickness and collagen content over 3 – 6 months (Goldberg 2021, Aesthet Surg J).
● Mild swelling or redness may last 24 – 48 h.
● Rare nodules or firmness are minimised by correct dilution and even distribution.
● Contraindications : Infection, pregnancy, autoimmune disease, prior filler in the same zone.
● Mild swelling or redness may last 24 – 48 h.
● Rare nodules or firmness are minimised by correct dilution and even distribution.
● Contraindications : Infection, pregnancy, autoimmune disease, prior filler in the same zone.
TREATMENT PLAN
● 2 sessions Spaced 6 weeks apart; annual maintenance.
● Procedure time : 45 – 60 min including consultation.
● Anaesthesia : Topical or local if required.
● Technique : Superficial subdermal fanning with cannula or micro-needle.
● Procedure time : 45 – 60 min including consultation.
● Anaesthesia : Topical or local if required.
● Technique : Superficial subdermal fanning with cannula or micro-needle.
RESULT TIMELINE
● Week 4 : Improved tone and elasticity.
● Month 3: Visible collagen lift.
● Month 12 – 18 : Long-term tissue strengthening.
● Month 3: Visible collagen lift.
● Month 12 – 18 : Long-term tissue strengthening.
EVIDENCE REFERENCES
● Goldberg DJ et al., Aesthet Surg J 2021.
● Rho NK et al., J Dermatolog Treat 2020.
● Rho NK et al., J Dermatolog Treat 2020.
FAQs
What is it?
Calcium hydroxyapatite in a high-dilution “wash” to stimulate collagen and improve firmness/texture.
Where?
Lower face, jawline, neck, décolletage, arms, knees.
How many sessions?
Often 2 spaced ~8 – 12 weeks, then review at 6 – 12 months.
Swelling?
Mild, with occasional temporary nodularity; massage instructions provided.
Pricing
Course of 2 sessions recommended for optimal collagen induction.