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Hyperdilute Radiesse London

Collagen Stimulation and Tissue Firming

- From £450 per session

Duration

45-60 minutes

Sessions

1

Pounds

Price

£450

Downtime

Minimal

Key Benefits

Stimulates natural collagen production
Improves skin firmness and elasticity
Enhances overall skin quality and texture
Reduces the appearance of fine lines
Helps improve mild to moderate skin laxity
Supports gradual skin tightening and remodelling
Improves the appearance of crepey skin
Provides natural-looking rejuvenation without significant volume
Can be used across both facial and body areas
Progressive, long-lasting skin-quality improvement

Target Areas

Face
Jawline & Lower Face
Neck
Décolletage
Hands
Upper Arms
Abdomen
Thighs & Buttocks
Areas of Skin Laxity & Crepey Skin

What It Is

Hyperdilute Radiesse® (calcium hydroxylapatite, Merz Aesthetics) is a regenerative injectable that improves skin elasticity and firmness through controlled collagen induction.

When diluted and placed in the superficial dermis, it remodels tissue gradually – improving tone and structure without creating bulk.

Mechanism Of Action

Contains CaHA microspheres suspended in gel carrier.
When diluted, microspheres act as a scaffold for fibroblast activation, leading to new type I & III collagen and elastin formation.
The carrier gel is absorbed, leaving firmer, naturally remodelled skin.
Onset : 4 - 6 weeks
Peak : 3 months
Duration : 12 - 18 months

Why Patients Choose Dr Hans Clinics

Doctor-led protocols using evidence-based dilution ratios.
CE-certified Merz product handled under aseptic conditions.
Ideal for face, neck, decolletage, arms, or knees.
Focus on measurable collagen change, not over-filling.

Evidence & Safety

Peer-reviewed research shows calcium hydroxylapatite significantly increases dermal thickness and collagen content over 3 - 6 months (Goldberg 2021, Aesthet Surg J).
Mild swelling or redness may last 24 - 48 h.
Rare nodules or firmness are minimised by correct dilution and even distribution.
Contraindications : Infection, pregnancy, autoimmune disease, prior filler in the same zone.

Treatment Plan

2 sessions Spaced 6 weeks apart; annual maintenance.
Procedure time : 45 - 60 min including consultation.
Anaesthesia : Topical or local if required.
Technique : Superficial subdermal fanning with cannula or micro-needle.

Result Timeline

Week 4 : Improved tone and elasticity.
Month 3: Visible collagen lift.
Month 12 - 18 : Long-term tissue strengthening.

Evidence References

Goldberg DJ et al., Aesthet Surg J 2021.
Rho NK et al., J Dermatolog Treat 2020.

Dr Hans Clinics : Protocol and workflow

Comprehensive Consultation & Skin Assessment

Medical History & Suitability Review

Skin Laxity & Quality Assessment

Clinical Photography & Treatment Mapping

Personalised Hyperdilute Radiesse Treatment Plan

Treatment Area Cleansing & Preparation

Controlled Hyperdilute CaHA Application

Controlled Hyperdilute CaHA Application

Collagen & Elastin Biostimulation

Post-Treatment Assessment

Aftercare & Recovery Guidance

Follow-Up & Progress Review

Maintenance Treatment Planning

Clinical Before & After Results

Pricing

Course of 2 sessions recommended for optimal collagen induction.

A Note on Transparency

PRF EZ Gel Biofiller is frequently marketed in ways that overstate what it does. Claims of long-lasting structural volume, permanent regeneration, or results comparable to dermal fillers aren’t supported by the current evidence. The published literature on plasma gel treatments is still relatively limited, and most studies are small and early in their design.

What we can say with reasonable confidence: PRF Biofiller improves subtle hollowing and early volume loss in suitable patients, delivers some regenerative stimulus through the PRF component, and does so without synthetic material. Results are real but modest, and maintenance is part of the treatment.

We think patients deserve to know that before they book. The consultation is where we work out whether this treatment makes sense for you, and if something else would work better, we’ll recommend that instead.

Our Treatment Specialists

Dr Hansel

Dr. Hansel Misquitta

Founder | Dr. Hans Clinics

MBBS | MSc Plastic & Reconstructive Surgery (UCL) | PGDip Bioethics (UNESCO Chair)

FAQ's

What is it?

Calcium hydroxyapatite in a high-dilution “wash” to stimulate collagen and improve firmness/texture.

Lower face, jawline, neck, décolletage, arms, knees.

Often 2 spaced ~8 – 12 weeks, then review at 6 – 12 months.

Mild, with occasional temporary nodularity; massage instructions provided.

Reviews

Semih
Before booking PRF EZ Gel for my under eyes, I had a lot of questions and concerns. Dr Hans took time to go through all of them properly and did not rush the consultation. She explained the treatment in a balanced way and set realistic expectations. The procedure itself was more comfortable than I imagined and the result looks very natural. My face looks more rested rather than noticeably treated, which was important to me.
Elene Gelashvili
I had a great experience with Dr. Hans. I wanted to do Ez gel under my eyes. She listened to my concerns and took her time to explain why it wouldn’t be suitable treatment for me. Instead we agreed to tighten my skin with Tixel - I had 3 sessions, very happy with the results.
Rachael Epstein
Absolutely the most knowledgeable and kindest doctor I’ve met. I’ve had injectables and PRF and soon tixel with her. She makes you feel so comfortable and confident. She will also say no and not just try to sell which is so important. She truly wants to improve the life of others which isn’t the case throughout the aesthetic industry (a lot of people try to exploit insecurities) and I used to work in it so I know! Thank you so much

Treatment Location

Firmness without filler.

Book your Hyperdilute Radiesse consultation at Dr Hans Clinics, London.

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