COMBINATION PROTOCOLS - hair & scalp
Combination Regenerative Protocols - Synergistic Collagen & Follicular Stimulation
From £380 per session
Some scalp conditions require more than one biological pathway to be activated.
Combination regenerative therapy at Dr Hans Clinics strategically layers autologous treatments (PRP / PRF) with biological adjuncts such as Biosomes, Growth Factors, and Exosome-inspired vesicles to achieve multi-level stimulation.
This approach doesn’t increase “volume” – it amplifies cellular communication, angiogenesis, and tissue repair, especially in complex or resistant cases of androgenetic alopecia, postpartum shedding, or post-inflammatory thinning.
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WHY COMBINE TREATMENTS?
Different regenerative materials target different points in the healing cascade:
● PRP / PRF – Supply autologous growth factors and fibrin scaffolding.
● Biosomes / Exosomes – enhance cell signalling and fibroblast metabolism
● GFs (Biomimetic Peptides) – Replenish epidermal and dermal communication.
When used together, these create a controlled, layered response that supports both short- and long-term follicular regeneration.
● PRP / PRF – Supply autologous growth factors and fibrin scaffolding.
● Biosomes / Exosomes – enhance cell signalling and fibroblast metabolism
● GFs (Biomimetic Peptides) – Replenish epidermal and dermal communication.
When used together, these create a controlled, layered response that supports both short- and long-term follicular regeneration.
EVIDENCE & SAFETY
● Gentile et al., Aesthet Surg J 2021 combined PRP + exosome therapy increases follicular density and calibre.
● Giordano et al., PRS Glob Open 2018 – PRF + exosome analogues enhance fibroblast proliferation and dermal elasticity.
● Kim et al., Stem Cells Transl Med 2021 – Exosome derivatives improve angiogenesis and dermal vascular networks.
All products used are CE-marked, sterile, and non-stem-cell formulations.
Performed by trained medical professionals in aseptic conditions.
● Giordano et al., PRS Glob Open 2018 – PRF + exosome analogues enhance fibroblast proliferation and dermal elasticity.
● Kim et al., Stem Cells Transl Med 2021 – Exosome derivatives improve angiogenesis and dermal vascular networks.
All products used are CE-marked, sterile, and non-stem-cell formulations.
Performed by trained medical professionals in aseptic conditions.
WHO BENEFITS MOST
● Patients with mixed-type alopecia (e.g., hormonal + inflammatory).
● Postpartum or post-stress shedding with prolonged telogen phase.
● Alopecia areata recovering from active phase (for follicular support).
● Trichotillomania recovery after behavioural therapy.
● Patients wanting visible scalp vitality improvement after PRP plateau.
● Postpartum or post-stress shedding with prolonged telogen phase.
● Alopecia areata recovering from active phase (for follicular support).
● Trichotillomania recovery after behavioural therapy.
● Patients wanting visible scalp vitality improvement after PRP plateau.
TREATMENT PLAN
● Consultation : Trichology review and treatment mapping.
● Course : 2 – 3 combination sessions, spaced 4 – 8 weeks apart.
● Session time : 45 – 60 min depending on number of layers combined.
● Maintenance : Single-session booster at 9 – 12 months.
Technique : Sequential injection – PRP or PRF first → followed by micro-needling with Biosomes / GFs for enhanced dermal delivery.
● Course : 2 – 3 combination sessions, spaced 4 – 8 weeks apart.
● Session time : 45 – 60 min depending on number of layers combined.
● Maintenance : Single-session booster at 9 – 12 months.
Technique : Sequential injection – PRP or PRF first → followed by micro-needling with Biosomes / GFs for enhanced dermal delivery.
AFTERCARE
● Avoid heat, washing, or exercise for 24 hours.
● Gentle rinse next day
● Continue prescribed topical peptides or serums.
● Gentle rinse next day
● Continue prescribed topical peptides or serums.
SAFETY & COMPLIANCE
● Combination therapies at Dr Hans Clinics use only autologous PRP/PRF and CE-marked cosmeceutical or peptide formulations.
● No stem-cell or unlicensed biologics are used.
● All procedures adhere to MHRA and ASA guidelines for aesthetic advertising and clinical safety.
● No stem-cell or unlicensed biologics are used.
● All procedures adhere to MHRA and ASA guidelines for aesthetic advertising and clinical safety.
DISCLAIMER
● Results vary between individuals and cannot be guaranteed; outcomes depend on diagnosis, follicular viability, and biological response.
COMMON COMBINATIONS
| Combination | Indication | Mechanism |
|---|---|---|
|
PRP + Exosomes (Biosomes) |
Androgenetic or telogen effluvium |
Dual activation: platelet GF release + exosome signal amplification |
|
PRF + Biosomes |
Post-inflammatory or stress-related thinning |
Collagen regeneration + mitochondrial repair |
|
PRP + Growth Factors |
Postpartum / diffuse shedding |
Enhances scalp hydration & keratinocyte recovery |
|
PRP + PRF |
Resistant diffuse loss or trichotillomania recovery |
Rapid release + sustained release of growth factors |
|
PRP + RF Microneedling + Biosomes |
Mature scalp or mixed-etiology thinning |
Collagen contraction + biological recovery |
Combination protocols are tailored after diagnostic assessment – not routine or “package” based.
TIMELINE OF RESULTS
| Stage | Clinical Change |
|---|---|
|
2 – 4 weeks |
Reduction in shedding; scalp texture improvement |
|
8 – 12 weeks |
Visible increase in thickness and resilience |
|
3 – 6 months |
Peak density and stabilised growth pattern |
|
12 months |
Maintenance phase; booster advised |
Pricing
Prices vary based on areas treated, material quantity, and indication severity.