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Facial Fat Transfer in London with SEFFILLER

A small-volume autologous fat transfer procedure using tissue collected from your own body.

- From £300 per session

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Need Help? --- Call us on +02035767676

Duration

45-60 minutes

Sessions

1/3

Pounds

Price

£300 - £850

Downtime

Mild swelling

Key Benefits

Uses your own fat for natural volume restoration
Improves skin quality, texture, and elasticity
Restores youthful facial contours
Long-lasting, natural-looking results
No synthetic fillers or foreign substances
Supports collagen production and tissue regeneration
Combines adipose-derived regenerative cells with structural fat grafting
Can treat multiple areas in a single procedure
Minimal scarring with minimally invasive fat harvesting

Target Areas

Face Volume Loss
Cheeks & Mid-Face
Temples
Under-Eye Hollowing
Jawline Definition
Nasolabial Folds
Marionette Lines
Hands Rejuvenation

Small-volume fat transfer using your own adipose tissue

SEFFILLER is a small-volume facial fat transfer procedure that uses a carefully collected amount of your own superficial adipose tissue.

The tissue is taken from a suitable donor area, prepared using the SEFFILLER system, and transferred to selected areas of the face.

Unlike dermal fillers, the treatment does not use a manufactured injectable gel. Unlike conventional facial fat grafting, it is designed around a relatively small, targeted harvest rather than larger-volume liposuction.

The result is a different approach to facial treatment: one that uses your own tissue and may be considered where selected volume loss, changes in soft tissue, or both contribute to the concern.

It is not intended to make every face fuller.
It is not a replacement for surgery.
And it is not a so-called “stem-cell facelift”

SEFFILLER AT A GLANCE

Treatment type
Small-volume autologous fat transfer
What is used
Your own prepared adipose tissue
Typical donor area
A suitable area of the abdomen, hip or outer thigh
Anaesthesia
Local anaesthetic is used in the standard protocol
Treatment approach
Small-volume harvest, preparation and targeted transfer
Main treatment goals
Selected facial volume loss and potential changes in tissue quality
Recovery
Swelling, bruising and tenderness can occur at both the donor and treated areas
Results
Develop as swelling settles and the transferred tissue stabilises
Consultation
Required to assess facial anatomy, donor-site suitability and treatment goals

A DIFFERENT APPROACH TO FACIAL VOLUME

Facial ageing is not simply a matter of losing collagen.
Over time, the face changes at several levels. Bone remodels. Fat compartments change. Soft tissues shift. Skin becomes thinner and behaves differently. (add image, make original image using ai or some software so can be cited)
For some people, the most noticeable change is a loss of volume.
The temples may appear more hollow. The transition between the lower eyelid and cheek may become more pronounced. The cheeks may look flatter. Weight loss may make the face appear more angular or depleted.
There are several ways to approach these changes.
Hyaluronic acid fillers or CaHa Fillers add a manufactured injectable material.
Biostimulators are used to produce a gradual tissue response.
PRP and PRF are prepared from blood.
SEFFILLER uses adipose tissue collected from the same patient.
That does not make it universally better. It makes it biologically and practically different.

WHAT SEFFILLER IS

SEFFILLER is a medical device system designed to assist the guided harvesting, preparation and autologous transfer of microfragmented subcutaneous adipose tissue.
YOUR OWN TISSUE
A small amount of superficial fat is collected from a suitable donor area.
GENTLE PREPARATION
The harvested tissue is washed and prepared according to the treatment protocol.
TARGETED TRANSFER
The prepared tissue is placed into selected areas in the same patient.
The standard SEFFILLER workflow uses a guided cannula and syringe system for the harvest. The tissue is washed using sterile saline and separated by gravity before being transferred into smaller syringes for grafting.
The procedure developed from the published SEFFI technique, or Superficial Enhanced Fluid Fat Injection, which has been studied in facial ageing and volume restoration.

MORE THAN VOLUME ALONE

Fat is often treated as though it is simply padding.
Biologically, it is much more complex.
Adipose tissue contains mature fat cells within a wider structural and cellular environment. This includes connective tissue, extracellular matrix, small blood vessels and mixed stromal and vascular cell populations.
This matters because the treatment is not simply placing an inert substance beneath the skin.
The transferred material is tissue.

WHAT IS PRESENT WITHIN ADIPOSE TISSUE

Diagram of adipose tissue highlighting five components: adipocytes, stromal/vascular elements, extracellular matrix, vascular-associated cells, and cellular signaling.

Dr Hans Clinics : Protocol and workflow

Comprehensive Consultation & Facial Assessment

Medical History & Suitability Review

Clinical Photography & Facial Analysis

Personalised Treatment Planning

Donor Fat Site Selection

Local Anaesthesia & Fat Harvesting

SEFFILLER® Fat Processing & Microfragmentation

Precision Fat Transfer & Regenerative Cell Injection

Symmetry Assessment & Final Refinement

Post-Treatment Aftercare

Follow-Up Review & Long-Term Maintenance

HOW THE TREATMENT WORKS

The visible outcome of facial fat transfer is not created by one single mechanism.
There are two parts to understand.
VOLUME
Transferred adipose tissue occupies space.
Where appropriate tissue persists after transfer, it may contribute to longer-term volume in the treated area.
The appearance immediately after treatment is not the final result. Early fullness also includes swelling, tissue fluid and the effects of the procedure.
TISSUE INTERACTION
Adipose tissue also contains cellular and structural components capable of interacting with the surrounding tissue environment.
Research across fat-derived procedures has investigated processes including cellular signalling, vascular responses and extracellular matrix remodelling.
These mechanisms are scientifically interesting and may help explain why changes in tissue quality have been reported after some fat-transfer procedures.
They should not, however, be turned into promises of guaranteed “regeneration”.
The biological rationale is credible. The visible response varies.

FROM HARVEST TO HEALING

Six-step infographic illustrating tissue graft process from selecting donor area to tissue integration for facial restoration.

WHAT CAN SEFFILLER BE USED FOR?

SEFFILLER may be considered where changes in facial soft tissue and volume contribute to the concern.
The aim is not to fill every line or make the face look fuller. Treatment is planned around the pattern of change, the anatomy beneath it and what a small-volume fat transfer procedure can realistically achieve.

AREAS THAT MAY BE CONSIDERED

UNDER-EYES AND LID-CHEEK JUNCTION
For selected patients with genuine hollowing or loss of soft-tissue support around the transition between the lower eyelid and cheek.
May be considered for:
under-eye hollowing
a pronounced lid-cheek transition
selected periocular volume loss
Important to know
Not every tired-looking under-eye is caused by volume loss. Eye bags, festoons, malar oedema, pigmentation and skin laxity require a different assessment and may not be improved by adding volume.
TEMPLES
For selected patterns of temporal hollowing that contribute to a gaunt or depleted appearance through the upper face.
May be considered for:
age-related temple hollowing
naturally lean temporal anatomy
selected volume loss following weight loss
Important to know
The temple is anatomically complex. The amount of correction required, previous treatments and the surrounding facial proportions all matter.
CHEEKS AND MIDFACE
For selected patients where loss of soft-tissue volume contributes to flattening, hollowing or a more depleted appearance.
May be considered for:
cheek volume loss
selected midface deficiency
submalar hollowing
facial volume loss following weight change
Important to know
Volume and lift are not the same thing. Fat transfer does not reproduce the effect of surgery and is not a solution for every form of tissue descent or skin laxity.
PERIORAL REGION
For selected changes around the mouth where soft-tissue loss is part of the concern.
May be considered for:
selected perioral volume loss
fine tissue changes around the mouth
localised soft-tissue deficiency
Important to know
The mouth is a highly mobile area. Lines around it may be influenced by movement, skin quality, dental and skeletal support, sun exposure and smoking as well as volume.
Published Micro-SEFFI research has included the perioral region, but the treatment should not be presented as a universal solution for lines around the mouth.
SELECTED FACIAL DEPRESSIONS AND SOFT-TISSUE DEFICIENCY
Fat transfer may also be considered for selected areas where localised soft-tissue deficiency contributes to an uneven transition or depression.
The suitability of these areas depends on:
the cause of the deficiency
the depth and extent of the area
previous procedures
the quality of the surrounding tissue
whether the expected correction is appropriate for a small-volume technique
CHANGES IN TISSUE QUALITY
SEFFI techniques have also been studied for changes associated with facial ageing beyond volume alone.
This does not mean that SEFFILLER should be marketed as a treatment that “regenerates the face”.
A more accurate explanation is that fat-derived procedures are being studied for their possible effects on the surrounding tissue environment as well as their role in volume restoration.
Visible changes in tissue quality may occur, but they are variable and cannot be guaranteed.

A FACE SHOULD NOT BE TREATED AS A COLLECTION OF EMPTY SPACES

A hollow temple, a tired under-eye and a flatter cheek may all appear to be problems of lost volume.
They are not necessarily the same problem.
The appearance of the face is influenced by:
Line drawing of a human skull inside an oval, with a three-dimensional outlined cube beneath it.
STRUCTURE
The underlying bone and skeletal proportions.
Educational diagram of a woman's face showing underlying facial muscles and tissue layers inside an oval, with a round dotted device below.
SOFT TISSUE
The amount, distribution and position of facial fat and other soft tissues.
SKIN
Thickness, elasticity, pigmentation and surface quality.
Oval portrait showing exposed facial muscles inside an oval frame, with a small smiling emoji beneath.
MOVEMENT
The repeated action of facial muscles.
Hourglass inside an oval frame with a small clock icon beneath, symbolizing time.
TIME
Ageing, weight change, hormones, illness and lifestyle.
Warning symbol: exclamation mark inside a circle, indicating attention needed
SEFFILLER is most relevant when soft-tissue volume loss or deficiency forms a meaningful part of the problem.
If the main concern comes from somewhere else, another treatment may make more sense.

THE TREATMENT MAP

Potential treatment areas are assessed individually during your consultation.
Upper face
Temples
Periocular region
Selected under-eye and lid-cheek hollowing
Midface
Cheeks, selected midface and submalar volume loss
Lower central face
Selected perioral soft-tissue deficiency
The highlighted areas show regions that may be assessed.
They do not represent a standard treatment pattern.
The areas selected, amount transferred and expected outcome depend on individual anatomy.
Infographic of a facial treatment map showing four numbered regions and colored zones on a front and side view of a woman's face, labeled upper face, periorbital region, midface, and lower central face.

VOLUME LOSS AFTER WEIGHT LOSS

Significant weight loss can change the face as well as the body.
The cheeks may flatten. The temples may become more hollow. The transition between the lower eyelid and cheek may become more visible. In some patients, the face simply looks more angular. In others, the dominant change is loose or descended tissue rather than a lack of volume.
These are different problems.
SEFFILLER may be considered where selected soft-tissue volume loss is an important part of the concern.
It is less likely to solve a problem caused mainly by:
significant skin laxity
tissue descent
prominent eye bags
ongoing rapid weight loss
unrealistic expectations of restoring a previous face exactly

TIMING MATTERS

If weight is still changing significantly, it may be sensible to delay volume restoration until the pattern of facial change is clearer.
Transferred adipose tissue is living tissue. Longer-term changes in body weight may therefore affect both the face and the appearance of the treated areas.
For patients using weight-management medication or undergoing active weight loss, treatment timing should be considered individually.

WHAT SEFFILLER IS NOT DESIGNED TO CORRECT

SIGNIFICANT LOOSE SKIN
Adding volume does not reproduce surgical skin removal or tissue repositioning.
PROMINENT EYE BAGS OR FESTOONS
These are not simply empty spaces. Adding volume may be unhelpful in the wrong anatomy.
PIGMENTATION
SEFFILLER is not a treatment for melasma, sun spots or pigment-related dark circles.
DYNAMIC EXPRESSION LINES
Lines caused mainly by repeated muscle movement require a different assessment.
A DESIRE FOR PRECISE, REVERSIBLE CORRECTION
Fat transfer does not offer the same immediate measurability or reversibility as a carefully selected hyaluronic acid filler.
EVERY SIGN OF FACIAL AGEING
No single procedure does.

TREAT THE CAUSE, NOT THE LABEL

“Tired eyes.”
“Ozempic face.”
“Sagging cheeks.”
“Deep smile lines.”
These are descriptions, not diagnoses of what has changed anatomically.
Two patients can use exactly the same words and require completely different treatment plans.
That is why the purpose of assessment is not to find somewhere to put fat.
It is to decide:
What has changed?
Is volume actually missing?
Would replacing it improve the face?
Is fat transfer the right way to do it?
Sometimes the answer will be yes.
Sometimes another treatment will offer more control.
Sometimes the problem is not volume at all.

WHO MAY BE SUITABLE FOR SEFFILLER?

SEFFILLER may suit patients who want to explore a small-volume fat transfer procedure and whose concern is genuinely related to facial soft-tissue volume loss or deficiency.
Suitability is not based on age alone.
It depends on three things:
THE FACE
Is volume loss actually part of the problem?
THE DONOR AREA
Is there enough suitable superficial adipose tissue to collect?
THE EXPECTATION
Does the patient understand how fat transfer differs from a precisely measured injectable product?
All three need to make sense.

SEFFILLER MAY BE WORTH CONSIDERING IF…

YOU HAVE GENUINE FACIAL VOLUME LOSS
This may include selected hollowing through the temples, periocular region, cheeks or midface.
The important word is genuine.
A face can look tired, older or less defined for many reasons. Adding volume only makes sense when loss or deficiency of soft tissue is meaningfully contributing to the appearance.
YOU HAVE BECOME MORE HOLLOW AFTER WEIGHT LOSS
Weight loss can alter facial volume as well as body composition.
For some patients, this creates localised hollowing through areas such as the temples or midface. In others, the more noticeable change is skin laxity or tissue descent.
SEFFILLER may be considered when volume loss is a significant part of the problem and the pattern of weight change is sufficiently stable to plan treatment sensibly.
YOU ARE INTERESTED IN USING YOUR OWN TISSUE
Some patients prefer to explore an autologous treatment rather than adding further manufactured injectable material.
SEFFILLER uses adipose tissue collected from and returned to the same patient.
That may be an important preference.
It should not, however, be confused with being:
risk-free
completely predictable
automatically more effective
suitable for every area
better simply because the tissue comes from your own body
Autologous describes where the tissue comes from. It is not a guarantee of outcome.
YOU ACCEPT THAT THE RESULT EVOLVES
Facial fat transfer is not judged like filler immediately after injection.
The early appearance includes swelling and other temporary effects of the procedure. The treated areas then change as recovery progresses.
A suitable patient understands that:
the first few days are not the final result
not all transferred tissue can be expected to persist
the final degree of correction cannot be predicted with absolute precision
further treatment may sometimes be considered
If you want an exact amount of immediately visible correction, another treatment may offer more control.
YOU ACCEPT A DONOR PROCEDURE
SEFFILLER requires tissue to be collected before it can be transferred.
That means recovery involves two sites:
the treated area and the donor area
Bruising, swelling, tenderness and temporary irregularity may occur at either.
This is a more involved process than arriving for a conventional injectable treatment.

THE IDEAL CANDIDATE IS NOT SIMPLY “SOMEONE WHO DOESN’T WANT FILLER”

This deserves its own visual break.
Avoiding dermal filler may be a reason to explore alternatives.
It is not, by itself, an indication for fat transfer.
A patient may dislike filler and still be better suited to:
no volume treatment at all
PRF
a biostimulator
a skin-directed treatment
surgery
observation and no intervention
The treatment should fit the anatomy.
Not the patient’s dislike of another product.

WHEN SEFFILLER MAY NOT BE THE RIGHT CHOICE

The concern Why another approach may be more appropriate
Significant loose or descended tissue
Adding volume does not reproduce surgical repositioning or skin removal
Prominent eye bags or festoons
These are not simply areas of missing volume
Pigmentation as the main concern
Fat transfer is not a pigment treatment
Dynamic expression lines
The primary cause is muscle movement rather than volume loss
A desire for exact, immediately measurable correction
Fat graft persistence is less predictable than placement of a measured injectable product
A need for reversibility
Transferred fat cannot be dissolved in the way hyaluronic acid filler usually can
Ongoing major weight change
Further changes in facial and body composition may alter treatment planning
No suitable donor area
The procedure requires adequate accessible superficial subcutaneous tissue
Unrealistic expectations
No fat-transfer technique can guarantee complete correction, fixed survival or a permanent result

WHAT IF I AM VERY SLIM?

Being slim does not automatically rule out SEFFILLER.
The procedure requires a relatively small amount of adipose tissue compared with conventional larger-volume fat grafting. However, there still needs to be a suitable donor area from which tissue can be collected appropriately.
Common areas assessed may include the:
abdomen
hip or flank region
outer thigh region
The manufacturer’s protocol requires adequate subcutaneous tissue at the harvesting site and identifies the abdomen, hips and trochanteric region among common donor areas.
For very lean patients, the question is not simply:
“Do you have any body fat?”
It is:
“Is there an appropriate area from which the required tissue can be harvested safely and according to the planned technique?”
This can only be assessed individually.
A patient should never be encouraged to gain weight purely to create a donor site for a cosmetic procedure.

WEIGHT STABILITY MATTERS

Transferred adipose tissue remains biologically responsive tissue.
Significant changes in body weight may therefore affect:
the untreated face
the donor area
the appearance of transferred tissue
the balance between treated and untreated facial areas
This does not mean a patient’s weight must remain identical forever.
It does mean that performing facial volume restoration during rapid or continuing major weight loss may make the longer-term result harder to plan.

A simple guide

Weight reasonably stable
Treatment may be assessed in the usual way.
Still losing weight gradually
Timing depends on the degree of change, facial changes and treatment goals.
Rapid or substantial ongoing weight loss
It may be sensible to wait until the facial pattern is clearer.
Planning major further weight loss
This should be discussed before treatment.
For patients using weight-management medication, the medication itself is not the only issue. The more relevant questions include the rate of weight change, nutritional status, general health and whether further substantial loss is expected.

PREVIOUS FILLER DOES NOT AUTOMATICALLY RULE OUT FAT TRANSFER

Many patients considering facial fat transfer have previously had dermal filler.
That history matters.
Before treatment, we need to understand:
which product was used
where it was placed
when it was injected
how much was used
whether any filler may still remain
whether there has been persistent swelling or other complications
whether previous filler was dissolved
Previous filler may alter the anatomy, tissue behaviour and interpretation of the area being assessed.
This is particularly relevant around the:
under-eyes
temples
cheeks
midface
Where necessary, previous treatment records or further assessment may be requested before a plan is made.
We do not assume that old filler has disappeared simply because several years have passed.

SMOKING AND NICOTINE

Smoking is a relevant consideration in any procedure involving tissue healing and graft survival.
The SEFFILLER device manual lists strong tobacco use as a relative contraindication.
Nicotine and smoking may adversely affect:
blood vessels
tissue oxygenation
healing
the environment into which tissue is transferred
Current smoking or nicotine use should therefore be disclosed during assessment.
This includes more than cigarettes.
Relevant nicotine exposure may include:
vaping with nicotine
nicotine pouches
nicotine replacement products
The appropriate plan depends on the individual procedure and health history.
We will give exact pre-treatment instructions in the pre-care section rather than turning this section into a lecture on cigarettes.

MEDICAL SUITABILITY

Because SEFFILLER involves tissue harvesting and transfer, the medical assessment is broader than for a simple skin treatment.
The manufacturer identifies several contraindications and cautions, including active infection at the harvest or graft site, malignancy at the relevant sites, pregnancy or breastfeeding, anticoagulant therapy or severe coagulation disorder, allergy to local anaesthetic, ongoing immunosuppressive therapy and significant physical debilitation. Strong tobacco use and non-resorbable material in relevant areas are listed as relative contraindications.

TREATMENT MAY NEED TO BE DELAYED, MODIFIED OR DECLINED IF YOU HAVE:

an active infection or significant skin problem in a planned treatment area
a relevant bleeding or clotting problem
medication that affects bleeding or healing
a significant allergy relevant to the procedure
an important medical condition affecting suitability or recovery
pregnancy or breastfeeding
previous permanent or non-resorbable material in a relevant area
a medical or treatment history that makes the procedure unsuitable
Do not stop prescribed medication in preparation for treatment unless the prescribing clinician has specifically advised you to do so.

EXPECTATIONS MATTER AS MUCH AS ANATOMY

A technically possible treatment is not always a good treatment.
SEFFILLER may not be appropriate where a patient expects:
every transferred fat cell to survive
an exact final volume
a guaranteed permanent result
complete removal of every hollow or line
no swelling or bruising
a facelift without surgery
to look exactly like a photograph, filter or previous version of themselves
The manufacturer’s own instructions state that outcomes vary according to factors including age, health, lifestyle, treatment site and operator experience, and that results may not be definitive.
A good treatment plan should survive contact with reality.

SUITABILITY AT A GLANCE

MAY BE WORTH EXPLORING
Selected facial soft-tissue volume loss
Appropriate donor tissue
Reasonably stable weight
Interest in an autologous tissue option
Acceptance of a donor procedure
Understanding that results evolve
Realistic expectations
MAY REQUIRE ANOTHER APPROACH OR FURTHER ASSESSMENT
Significant loose or descended tissue
Prominent eye bags, festoons or persistent oedema
Pigmentation as the primary concern
Major ongoing weight change
No suitable donor area
Relevant medical contraindications
A need for exact, reversible correction
Expectations that the procedure cannot realistically meet

THE PURPOSE OF THE CONSULTATION

WHAT HAS ACTUALLY CHANGED?

Volume, skin, structure, movement, tissue position, or a combination?

Not every hollow should be filled.

Your own tissue is one option, not automatically the best option.

If the answer is no, the treatment should not go ahead.

RESULTS AND TIMELINE

SEFFILLER does not have a single “results day”.
The appearance changes in stages.
Immediately after treatment, the face may look fuller because the treated area contains the transferred tissue alongside swelling and fluid from the procedure. Over the following weeks, those early effects settle. The longer-term result becomes clearer only after the tissue has had time to stabilise.
This is why a before-and-after photograph taken immediately after facial fat transfer tells you very little about the final outcome.

HOW RESULTS DEVELOP

DAY 0

THE TREATMENT DAY

The treated area may look fuller than expected.
This early appearance can reflect:
transferred tissue
swelling
local fluid
the immediate effects of treatment
The donor area may feel tender and can develop bruising.
Do not judge the result yet.
DAYS 1 TO 7

THE EARLY RECOVERY PHASE

Swelling and bruising are usually most relevant during the early recovery period.
The face may look:
uneven
puffy
fuller than expected
different from one side to the other
This does not necessarily represent the final result.
The donor area may also remain:
tender
bruised
swollen
temporarily firm or irregular
Recovery varies between patients and between treatment areas.
WEEKS 2 TO 6

SETTLING

Much of the obvious early swelling should be reducing, although the timing varies.
The treated areas begin to look and feel more settled.
During this period, the appearance may continue to change as:
swelling resolves
temporary fluid reduces
the transferred tissue undergoes its early biological response
tissue that does not persist is gradually resorbed
The result may appear less full than it did immediately after treatment.
That does not automatically mean the procedure has “failed”. Early post-treatment fullness was never the final result.
AROUND 3 MONTHS

A MORE MEANINGFUL ASSESSMENT

By this stage, the result is usually more useful to assess than it was during the early recovery period.
The questions become:
how has the treated area settled?
what degree of correction remains?
how does it fit with the rest of the face?
has the donor area recovered appropriately?
is any further treatment worth considering?
The exact review schedule depends on the individual treatment plan.
LONGER TERM

THE RESULT CONTINUES TO AGE WITH YOU

Where transferred adipose tissue persists, it remains part of a living and changing face.
The result can therefore continue to be influenced by:
ageing
weight change
hormonal change
illness
smoking and nicotine exposure
changes in surrounding facial tissues
Facial fat transfer does not stop the ageing process.
It does not lock the face at the age or weight at which the procedure was performed.

THE RESULT IS NOT ONE THING

Three-panel infographic showing stages: 1) Early fullness — What you see first, with a face and arrows; 2) Settling — What changes, face image; 3) Longer-term result — What remains, face image.

WHAT HAPPENS TO THE TRANSFERRED FAT?

This needs to be explained simply because it is the part patients misunderstand most.
Not all transferred adipose tissue can be expected to persist.
After transfer, the graft enters a new tissue environment. Its longer-term behaviour is influenced by the condition of the transferred tissue, the recipient area and individual patient factors.
Some transferred tissue may persist.
Some may not.
The visible result is the outcome of that process after the early swelling has settled.
Diagram of adipose tissue transfer in four stages: transfer, early phase, settling and integration, and long-term outcome with cross-sectional skin views and fat clusters.

HOW MUCH OF THE FAT SURVIVES?

There is no honest universal percentage.

This is one place where I want us to be firmer than competitor websites.
You may see clinics quote a fixed survival rate for facial fat transfer.
The problem is that graft persistence varies according to multiple factors, including:
the patient
the donor tissue
tissue handling
the recipient area
the amount and pattern of placement
smoking and nicotine exposure
general health
weight change
individual biology
Different fat-transfer techniques also cannot simply borrow survival percentages from one another.
A study of one harvesting, processing and placement method does not automatically tell us exactly how much tissue will persist after every SEFFILLER procedure.
For that reason, we do not promise that:
a fixed percentage will survive
all transferred tissue will remain
the immediate post-treatment volume will be maintained
every patient will retain the same degree of correction
The manufacturer also states that outcomes may vary according to patient and procedural factors and that results may not be definitive.

HOW LONG CAN THE RESULTS LAST?

There is no single expiry date.
Where transferred adipose tissue successfully persists, the result may last beyond the temporary effects of swelling and early recovery.
However, the visible result can continue to change because:
Analog clock showing 3:00 on a white background with a black frame, minute hand at 12 and hour hand at 3 THE FACE CONTINUES TO AGE
Bone, fat, skin and supporting tissues continue to change.
Icon of a bathroom scale with a round dial and two footprint outlines inside a rounded square base. BODY WEIGHT CAN CHANGE
Transferred adipose tissue remains responsive to the body’s wider biology.
Stylized black DNA double helix illustration used as a science symbol. THE ORIGINAL DEGREE OF GRAFT PERSISTENCE VARIES
Not every patient retains the same amount of visible correction.
Profile avatar icon: a simple user silhouette inside a circle with bold outline THE TREATED AREA MATTERS
Different facial regions have different anatomy, movement and tissue characteristics.
Black bullseye target with three rings and crosshair lines. THE TREATMENT GOAL MATTERS
A subtle change in tissue quality is not measured in the same way as visible volume restoration.
For these reasons, we do not describe SEFFILLER as a treatment with a guaranteed fixed duration.
We also do not describe it as “permanent filler”.

WHAT HAPPENS IF I GAIN OR LOSE WEIGHT?

This deserves a prominent visual section because it is both clinically important and highly relevant to patient search behaviour.

IF YOUR WEIGHT DECREASES

Further weight loss may reduce facial volume, including in areas surrounding the treatment.
The balance of the face may therefore continue to change.

IF YOUR WEIGHT INCREASES

Persisting adipose tissue may respond to wider changes in body composition.
This does not mean a small amount of transferred facial fat will suddenly behave like an expanding balloon. It means that living adipose tissue remains biologically responsive.

IF YOUR WEIGHT IS CHANGING RAPIDLY

The final facial pattern may still be evolving.
In some patients, waiting until weight is more stable may allow more sensible treatment planning.
The goal is not a perfect number on the scales. It is enough stability to understand the face we are actually planning to treat.

WILL I NEED MORE THAN ONE TREATMENT?

Possibly.
A single procedure may be sufficient for some treatment goals. In other patients, further treatment may be discussed after the initial result has settled.
The need for another treatment may depend on:
the starting anatomy
the area treated
the amount of correction sought
the degree of tissue persistence
ongoing ageing or weight change
whether the first treatment achieved a result worth building on
A second treatment should not be booked automatically before the first result can be properly assessed.
The manufacturer’s patient information refers to possible repeat treatment at intervals depending on the individual and treatment goals.
For the website, however, I would not repeat the brochure’s “4, 6 or 12 months” as a standard schedule unless your training confirms exactly how this applies to facial SEFFILLER in current practice.
That wording could make the treatment sound like a routine subscription package when the actual need should be individually assessed.

WHAT SHOULD A GOOD RESULT LOOK LIKE?

Not “done”.
Not swollen.
Not a face in which every hollow has been erased.
A good result should make sense within the rest of the face.
Depending on the treatment plan, that may mean:
The aim should be proportion, not maximum volume.
a softer transition between facial areas
less obvious localised hollowing
restoration of selected soft-tissue volume
a less depleted appearance
subtle changes in aspects of tissue quality
The aim should be proportion, not maximum volume.

RESULTS AT A GLANCE

What to expect
Immediately after
Fullness, swelling and possible bruising
First week
The appearance may be puffy, uneven or asymmetric while recovering
Following weeks
Swelling reduces and the result continues to change
Around 3 months
A more meaningful assessment of the settled result may be possible
Longer term
The appearance continues to be influenced by ageing, weight and individual biology
Guaranteed survival percentage?
No
Guaranteed permanent result?
No
Further treatment possible?
Yes, where appropriate after assessment

YOUR SEFFILLER TREATMENT JOURNEY

SEFFILLER involves two areas of the body: the donor area, where a small amount of adipose tissue is collected, and the treatment area, where the prepared tissue is transferred.
The exact plan varies between patients, but the journey follows a series of distinct stages.

01. CONSULTATION AND TREATMENT PLANNING

The first step is deciding whether fat transfer is actually the right treatment.
The assessment considers:
the change you want to address
whether volume loss is genuinely contributing to it
facial anatomy and proportions
skin and soft-tissue quality
previous filler, biostimulators or surgery
medical history and medication
smoking and nicotine use
current or planned weight change
suitability of a potential donor area
the degree of correction you are hoping to achieve
The treatment plan should be specific to the face in front of us.
Not every hollow needs filling. Not every area of volume loss needs fat. And not every patient who wants to avoid dermal filler is automatically better suited to SEFFILLER.
Before treatment, the plan should answer:
Where is treatment being considered?
Why is fat transfer being considered for that area?
Where can suitable donor tissue be collected?
What degree of change is realistic?
What are the alternatives?

02. CHOOSING THE DONOR AREA

A suitable area of superficial subcutaneous adipose tissue is identified.
Common potential donor areas include the:
ABDOMEN
A commonly assessed area where sufficient superficial subcutaneous tissue is present.
HIP OR FLANK REGION
May provide a suitable donor site depending on individual anatomy.
OUTER THIGH REGION
Another potential area where appropriate superficial adipose tissue may be available.
The choice is not based on where a patient most wants to lose fat.
This is not a body-contouring procedure.
Only the amount of tissue required for the planned treatment is collected, and patients should not expect visible slimming or reshaping of the donor area.
The SEFFILLER device instructions identify the abdomen, hips and trochanteric region among commonly used harvesting areas and require adequate subcutaneous tissue at the selected site.

TWO AREAS. TWO RECOVERIES.

THE DONOR AREA THE TREATMENT AREA
Where tissue is collected
Where prepared tissue is transferred
Small skin entry point
Needle or cannula entry points
May bruise or feel tender
May swell or bruise
Dressing required
Recovery depends on the area treated
Patients often focus on the face and forget about the donor site. Both areas form part of the procedure and recovery.

03. PREPARING FOR THE PROCEDURE

On the day of treatment, the planned donor and treatment areas are reviewed.
Before proceeding:
the treatment plan is confirmed
relevant medical information and medication are reviewed
the donor area is reassessed
the areas being treated are documented
the skin is checked for any reason to delay treatment
The procedure is performed using aseptic technique.
The manufacturer’s protocol requires careful preparation of both the harvesting and grafting areas and maintenance of sterile conditions during the procedure.
Detailed instructions on medication, alcohol, smoking, skincare and what to bring will appear in the Preparing for Your Treatment section later on this page.

04. LOCAL ANAESTHESIA

The standard SEFFILLER protocol uses local anaesthesia at the donor area.
A small skin opening is created for the harvesting cannula, and local anaesthetic solution is introduced into the planned collection area.
The manufacturer’s procedure includes a waiting period after infiltration before the tissue harvest begins.
Patients may feel:
the initial anaesthetic injections
pressure
movement
pulling or unusual sensations during the harvest
We should not describe the procedure as painless.
Comfort varies between patients and between donor areas.

05. SMALL-VOLUME TISSUE HARVEST

Once the area has been prepared, a small amount of superficial adipose tissue is collected.
Cross-section of skin showing a harvesting tool labeled SEFFILLER removing a small amount of superficial adipose tissue from the subcutaneous layer in an infographic style.

06. WASHING AND PREPARING THE TISSUE

After collection, the adipose tissue is prepared before transfer.
In the standard SEFFILLER workflow, the harvested tissue is combined with sterile saline and allowed to separate by gravity.
Step-by-step tissue preparation: harvest tissue, wash with sterile saline, gravity separation, remove wash fluid, retain tissue, transfer into syringes for grafting.

07. PREPARING THE TISSUE FOR TRANSFER

Once washed, the tissue intended for grafting is transferred into smaller syringes.
The manufacturer’s standard protocol specifies that the tissue is transferred while excluding the oily layer at the top.
The tissue can then be prepared for placement into the selected treatment areas.
The exact:
amount used
areas treated
placement pattern
instrument used for transfer
depend on the treatment plan and trained clinical technique.
There is no standard number of syringes that every face should receive.

08. TRANSFERRING THE TISSUE

The prepared tissue is placed into the agreed treatment areas.
Illustration comparing a single large tissue deposit to many small, precisely placed parcels for targeted treatment.
Black bullseye target with three rings and crosshair lines. The amount and pattern of placement depend on the anatomy, treatment area and intended degree of correction.
More tissue is not automatically better.
Overcorrection is not a substitute for planning around the uncertainty of graft persistence.
The aim is not to see how much fat can be placed.
The aim is to use an appropriate amount for the area and treatment goal.

09. IMMEDIATELY AFTER TREATMENT

At the end of the procedure, both the donor area and treated area are assessed.
A dressing is applied to the donor site.
You may notice:
AT THE DONOR AREA
tenderness
swelling
bruising
a small amount of blood spotting on the dressing
AT THE TREATED AREA
swelling
fullness
bruising
tenderness
temporary unevenness or asymmetry
The manufacturer’s patient information states that a small amount of bleeding visible on the donor-site dressing may occur during the first 12 hours.
The face may look fuller than the planned longer-term result.
That early appearance should not be used to judge the outcome.

YOUR TREATMENT JOURNEY AT A GLANCE

Line drawing of a doctor holding a clipboard and talking to a patient inside a circular frame. CONSULT
Assess the concern, anatomy, alternatives and suitability
Profile icon: side view of a woman's face inside a circle, simple line drawing with a ponytail buttress detail. PLAN
Select the treatment areas and a suitable donor site
Hand sanitizer bottle with a shield displaying a medical cross inside a circular border, symbolizing health protection. PREPARE
Clean and prepare both areas using aseptic technique
Syringe and vaccine vial inside a circular border ANAESTHETISE
Use local anaesthesia according to the procedure plan
Syringe angled above a beaker containing pills, all inside a circular border. HARVEST
Collect a small amount of superficial adipose tissue
Diagram of a chemical reaction: a liquid in the left test tube is converted to gas bubbles in the right test tube, shown by an arrow. PREPARE THE TISSUE
Wash, separate and transfer the tissue for grafting
Line drawing of a woman's face inside a circle, with dotted lines under the eyes indicating treatment areas. TREAT
Place the prepared tissue into selected areas
Calendar icon with a checkmark indicating a confirmed date or event RECOVER
Allow swelling and bruising to settle
Clipboard with a checkmark, indicating a completed task or approval. REVIEW
Assess the result after an appropriate period of recovery

HOW LONG SHOULD I EXPECT TO BE AT THE CLINIC?

The treatment itself is only one part of the appointment.
Time is also needed for:
reviewing the plan
preparation
local anaesthesia
the waiting period before harvesting
tissue collection
transfer
dressings
post-treatment checks
The manufacturer’s patient information describes an average procedure duration of approximately 40 minutes.
Appointment time varies according to the treatment plan and areas being treated. You will be given an expected appointment duration before treatment.
After your training and first proper cases, we can replace that with a realistic clinic-specific range. If it takes 75 minutes in real life, the website should not promise 40 because a brochure did.

BEFORE YOU LEAVE

Before leaving the clinic, you should know:
how to care for the donor-site dressing
what swelling and bruising may be expected
which activities to avoid
when you can wash or shower
what medication or skincare instructions apply
which symptoms require urgent contact
how and when follow-up will take place
You should also have a clear way to contact the clinic if you are concerned during recovery.

RECOVERY AND DOWNTIME

Recovery after SEFFILLER involves two separate areas:
the donor area, where the adipose tissue was collected.
the face, where the prepared tissue was transferred.
They do not necessarily recover at the same rate.
The amount of swelling and bruising varies according to the areas treated, the amount of tissue transferred and individual healing. Some patients may feel comfortable returning to normal daily activities relatively quickly. Others may prefer more time before work or social events.
If you have an important event, photographs or travel planned, do not schedule treatment too close to it.

WHAT TO EXPECT AFTER TREATMENT

THE TREATED AREA

You may experience:
swelling
bruising
tenderness
temporary firmness
fullness
unevenness while swelling settles
temporary asymmetry during early recovery
The face may initially look more corrected than the eventual result.
This is expected to change.

THE DONOR AREA

You may experience:
bruising
tenderness
swelling
temporary firmness or irregularity
discomfort with pressure or movement
a small amount of spotting on the dressing
The donor area is not simply the place the treatment came from. It is a second treatment site and needs its own recovery time.

YOUR RECOVERY, DAY BY DAY

FIRST 24 HOURS

Protect both treatment areas
Swelling and tenderness may begin during the first day.
A small amount of blood spotting on the donor-site dressing can occur. The manufacturer’s patient information notes that this may be seen during the first 12 hours.
During this period:
follow the instructions given for the donor-site dressing
avoid pressing, rubbing or massaging the treated areas unless specifically advised
avoid strenuous exercise
avoid unnecessary heat exposure
take only medication that has been approved or advised for you
contact the clinic if something feels significantly different from what was explained
The face may look fuller or more uneven than expected.
This is far too early to assess the result.

DAYS 2 TO 3

Swelling and bruising may be more noticeable
For some patients, swelling is not at its most obvious immediately after treatment.
It may become more noticeable during the first few days before beginning to settle.
You may notice:
facial puffiness
bruising becoming darker or more visible
tenderness at the donor area
temporary asymmetry
a feeling of firmness or fullness
This can be inconvenient.
It is not useful to pretend otherwise.
If you need to look completely normal for a wedding, television appearance, court hearing or first date with someone whose photographs were suspiciously good, give yourself more recovery time than the minimum.

DAYS 4 TO 7

Early recovery continues
Swelling and bruising should begin to evolve, although the pace varies considerably.
Some patients may feel ready to return to work and social activities earlier. Others may still have visible swelling or bruising.
During this stage:
the face may still look different from side to side
bruising may change colour as it resolves
the donor area may remain tender
the treated area may still feel different to touch
The result is still settling.

WEEKS 2 TO 6

The face begins to look more settled
Much of the obvious early recovery should be improving, although some changes may take longer.
The treated area may appear less full than it did immediately after the procedure.
This is expected.
Early post-treatment volume included swelling and fluid. The appearance after those have reduced is more relevant than the appearance on treatment day.
The donor area should also continue to settle.

THE FOLLOWING MONTHS

The longer-term result becomes clearer
Once the early recovery phase has passed, attention shifts from swelling and bruising to the actual treatment outcome.
This is when it becomes more meaningful to assess:
the degree of correction
the balance between treated and untreated areas
how the tissue has settled
whether the result is appropriate for the face
whether any further treatment should even be considered
Further treatment should not be planned simply because the face looked fuller on day one than it does later.
Day one was never the final result.

HOW MUCH DOWNTIME SHOULD I PLAN FOR?

There is no single number that applies to everyone.
A better way to plan is by asking what you need to be ready for.
Your plans What to consider
Working from home
You may feel able to work before you are socially presentation-ready
Office work
Visible swelling or bruising may still be present
Public-facing work
Allow more flexibility in case recovery is noticeable
Important social event
Do not rely on the shortest possible recovery estimate
Wedding or major photographs
Leave a generous margin between treatment and the event
Travel
Discuss the timing before booking treatment
The clinic should give you an individual estimate based on the areas being treated.
No website can guarantee exactly when another person will stop noticing your swelling.

WORK AND SOCIAL PLANS

Some patients may return to normal daily activities relatively quickly.
That does not mean the treatment has no downtime.
There is a difference between:
being medically well enough to work
and
looking exactly as you did before treatment
If your work involves:
public speaking
filming
photography
close client contact
an important presentation
plan more conservatively.

EXERCISE

Strenuous exercise should be avoided during the early recovery period.
Exercise can increase:
blood flow
swelling
bruising
discomfort
The exact timing for returning to:
gym training
running
swimming
contact sport
heavy lifting
depends on the extent of the procedure and your recovery.
You will be given individual instructions after treatment.

SLEEPING

The treated areas should be protected from unnecessary pressure during early recovery.
Depending on the areas treated, you may be advised to:
sleep on your back initially
keep your head slightly elevated
avoid sleeping directly on a treated facial area
This is particularly relevant when treatment involves areas that may be compressed by side sleeping.
The exact advice should follow the treatment performed.

SHOWERING AND THE DONOR-SITE DRESSING

The donor site has a small skin entry point and dressing.
Instructions should cover:
how long to keep the initial dressing in place
when showering is permitted
whether a replacement dressing is required
what to do if the dressing becomes wet or heavily soiled
The exact instructions should follow the procedure and dressing used.
The manufacturer’s patient information states that some blood may be visible on the dressing during the first 12 hours and gives specific advice on replacing the dressing if necessary.

MAKEUP AND SKINCARE

The face should be treated gently during early recovery.
Patients should not immediately:
rub or massage the treated areas
use aggressive exfoliating products
apply retinoids or strong acids
use home microneedling devices
apply unnecessary pressure to the treatment sites
The timing of makeup depends on:
the areas treated
the condition of the skin
the entry points used
individual recovery
You will be given instructions appropriate to your procedure.

ALCOHOL

Alcohol can contribute to dehydration and may worsen bruising or swelling in some patients.
It is sensible to avoid alcohol during the immediate recovery period and follow the instructions provided for your treatment.
The exact pre-treatment advice belongs in the Preparing for Your Treatment section.

HEAT, SAUNAS AND STEAM ROOMS

During early recovery, avoid unnecessary exposure to:
saunas
steam rooms
very hot baths
intense heat treatments
Heat may increase swelling and discomfort.
Return gradually once the early recovery period has passed and the treated areas are healing normally.

FACIAL MASSAGE AND OTHER TREATMENTS

Do not massage the treated facial areas unless you have specifically been instructed to do so.
Also avoid booking other facial procedures too close to SEFFILLER without discussing the timing first.
This includes:
facial massage
lymphatic massage of the treated face
facials
microneedling
energy-based treatments
lasers
radiofrequency
ultrasound-based treatments
other injectable procedures
The correct interval depends on:
the treatment performed
the area treated
recovery
the proposed next procedure
There is no sensible universal rule that every treatment can simply restart after two weeks.

FLYING AND TRAVEL

If you are planning to travel soon after treatment, discuss this before booking.
Travel may affect:
access to follow-up
management of unexpected concerns
swelling and comfort
the ability to return for assessment if needed
For longer journeys, individual risk factors may also need to be considered.
The website should not promise that flying is automatically fine after a fixed number of hours.
The treatment plan and the patient matter.

WHAT IS EXPECTED, AND WHAT NEEDS REVIEW?

COMMON DURING EARLY RECOVERY
swelling
bruising
tenderness
temporary firmness
temporary unevenness
asymmetry while swelling settles
discomfort at the donor site
a small amount of spotting on the donor-site dressing
These symptoms should be considered in the context of how severe they are and whether they are improving.
CONTACT THE CLINIC PROMPTLY IF YOU ARE CONCERNED ABOUT:
increasing rather than improving pain
rapidly worsening swelling
marked redness or heat
discharge or other signs of possible infection
persistent bleeding
significant colour change in the skin
new blistering or skin breakdown
increasing asymmetry that appears unusual
fever or feeling systemically unwell
any symptom that is severe, rapidly changing or was not expected from your aftercare discussion
Patients should not wait for a routine review if they are worried that something is wrong.

SEEK URGENT MEDICAL HELP

Seek urgent medical attention for symptoms such as:
difficulty breathing
chest pain
collapse
severe allergic symptoms
sudden significant visual disturbance
rapidly progressive severe symptoms
This list is not exhaustive. If you believe you are experiencing a medical emergency, seek urgent medical assistance rather than waiting for a routine clinic response.

RECOVERY AT A GLANCE

Stage What may be happening
First 24 hours
Swelling, tenderness and early bruising may begin
Days 2 to 3
Swelling or bruising may become more noticeable
Days 4 to 7
Early recovery continues and appearance may remain variable
Weeks 2 to 6
The face and donor area continue to settle
Following months
The longer-term result becomes more meaningful to assess
Recovery varies. The shortest recovery you read about online should not become the deadline you expect your own body to meet.

PLANNING AROUND THE PROCEDURE

Black briefcase icon representing business or professional services. WORK
Plan according to how visible you can afford swelling or bruising to be, not simply whether you can physically answer emails.
Camera icon button EVENTS
Leave a generous margin before important photographs, weddings and major social occasions.
Black silhouette of a fixed-wing airplane angled upward, like an icon. TRAVEL
Discuss travel plans before treatment, particularly if they would limit access to follow-up.

PREPARING FOR YOUR SEFFILLER TREATMENT

Good preparation is not about following a dramatic list of restrictions.
It is about arriving for treatment with:
an accurate medical history
no important information withheld
the donor and treatment areas in suitable condition
realistic plans for recovery
Your individual instructions may differ depending on your health, medication, donor area and treatment plan.

2 TO 4 WEEKS BEFORE

KEEP US UPDATED ABOUT YOUR HEALTH
Tell the clinic if there has been any change in your:
health
medication
allergies
pregnancy or breastfeeding status
recent surgery or medical treatment
tendency to bleed or bruise
smoking or nicotine use
Also tell us about any previous treatment in the areas being considered, including:
dermal filler
permanent or non-resorbable filler
biostimulators
fat transfer
surgery
threads
energy-based treatments
previous complications
Previous treatment does not automatically prevent SEFFILLER, but it may change the assessment or treatment plan.
KEEP YOUR WEIGHT PLANS REALISTIC
If you are actively losing weight, planning major further weight loss or have recently had a significant change in weight, tell us before treatment.
This includes weight loss with:
diet and lifestyle changes
weight-management medication
bariatric procedures
illness
You do not need to maintain one exact number on the scales.
However, major ongoing changes in facial and body composition may affect both donor-site planning and the longer-term appearance of the face.
Do not deliberately gain weight to create a donor area for treatment.
SMOKING AND NICOTINE MATTER
Smoking is relevant to tissue healing and the environment into which adipose tissue is transferred.
The SEFFILLER device information lists strong tobacco use as a relative contraindication.
Tell us if you use:
cigarettes
nicotine-containing vapes
nicotine pouches
nicotine replacement products
Do not simply answer “non-smoker” if you vape nicotine every day. Your blood vessels are not impressed by semantics.
The exact advice on reducing or stopping nicotine should be given individually, particularly if you use prescribed or medically supervised nicotine replacement.

7 DAYS BEFORE

DO
KEEP WELL HYDRATED
Normal hydration supports general wellbeing and recovery.
There is no need for extreme water loading or a special “detox”.
EAT NORMALLY
Unless you have been given different instructions for a specific reason, maintain a normal balanced diet.
This is not a treatment to prepare for with:
fasting
crash dieting
juice cleanses
severe calorie restriction
Adequate nutrition matters for recovery.
PLAN FOR DOWNTIME
Consider:
work
filming or photography
weddings and social events
exercise
travel
childcare
anything that requires you to look completely normal immediately
Do not plan around the best-case recovery photograph you found online.
TELL US
Contact the clinic before your appointment if you:
become unwell
develop a fever
start antibiotics
develop a skin infection
develop a rash or inflammatory skin flare in a planned treatment area
have a dental infection or significant dental procedure
start a new medication
have an unexpected change in your health
Treatment may need to be postponed.
Moving an appointment is irritating.
Treating through an avoidable problem is more irritating.
DO NOT STOP MEDICATION YOURSELF
Some medicines and supplements can affect bleeding, bruising or healing.
This does not mean you should stop them because a website told you to.
Tell us about:
anticoagulants
antiplatelet medication
anti-inflammatory medication
prescribed steroids
immunosuppressive treatment
supplements
herbal products
any medication relevant to bleeding or healing
Do not stop prescribed medication unless the clinician responsible for that medication has specifically advised you to do so.

MEDICATIONS AND SUPPLEMENTS

WHY DO WE ASK?
Some medicines and supplements may affect:
bleeding
bruising
healing
infection risk
suitability for local anaesthetic
overall procedural risk
The answer is not to produce one universal internet blacklist.
The answer is to review what you actually take.
Bring or provide an up-to-date list of:
prescription medicines
over-the-counter medicines
vitamins
herbal products
supplements
If you are unsure whether something matters, tell us anyway.

48 HOURS BEFORE

AVOID ALCOHOL
Alcohol may contribute to dehydration and may worsen bruising or swelling in some patients.
Avoid alcohol in the immediate period before treatment according to the instructions provided for your procedure.
DO NOT IRRITATE THE TREATMENT AREAS
Avoid unnecessary irritation of the planned facial and donor areas.
Do not deliberately:
exfoliate aggressively
use home microneedling devices
wax over a planned treatment area
use strong chemical peels
have another invasive cosmetic procedure
If you develop broken skin, significant irritation or inflammation, tell the clinic.
THINK ABOUT CLOTHING
Wear comfortable clothing that allows practical access to the planned donor area.
Depending on the donor site, this may mean avoiding:
tight waistbands
restrictive clothing
delicate clothing you would be devastated to stain
A small amount of fluid or blood spotting can occasionally occur at the donor-site dressing during early recovery.
White silk trousers are a lifestyle choice. They are not an ideal procedural choice.

THE DAY BEFORE

Eat normally
Keep normally hydrated
Avoid alcohol as instructed
Check that you feel well
Make sure the clinic knows about any new medication or illness
Prepare comfortable clothing
Check your travel arrangements
Make sure you have time to recover afterwards
Do not crash diet
Do not stop prescribed medication without medical advice
Do not arrive with an undisclosed infection or illness
Do not schedule the procedure immediately before an important event

ON THE DAY OF TREATMENT

EAT AND DRINK NORMALLY
Unless you have specifically been told otherwise, do not arrive dehydrated or after unnecessary fasting.
The standard SEFFILLER procedure uses local anaesthesia.
Your individual instructions take priority if there is a clinical reason for them to differ.
ARRIVE WITH CLEAN SKIN
Where practical, arrive with the planned treatment areas clean.
Avoid applying unnecessary products to the areas being treated.
For facial treatment, this may mean avoiding:
heavy makeup
self-tan
thick occlusive skincare
The skin will still be prepared appropriately before the procedure.
WEAR PRACTICAL CLOTHING
Your clothing should allow access to the planned donor area without unnecessary difficulty.
The donor area may be the:
abdomen
hip or flank region
outer thigh region
The actual area will have been discussed during planning.
BRING AN ACCURATE MEDICATION LIST
Especially if anything has changed since consultation.
Do not assume:
“It is only a supplement.”
or
“I only take it occasionally.”
means it is irrelevant.
ALLOW ENOUGH TIME
Do not schedule the appointment between two meetings as though you are having your eyebrows threaded.
Time may be needed for:
final review
preparation
local anaesthesia
tissue harvesting
tissue preparation
transfer
dressings
post-treatment checks
Appointment duration varies with the treatment plan.

WHAT MAY CAUSE YOUR TREATMENT TO BE POSTPONED?

Treatment may need to be delayed if, for example, you have:
Outline of a stethoscope, a medical examination tool (silhouette). AN ACTIVE INFECTION
At the donor site, treatment area or elsewhere where it creates a relevant clinical concern.
Adhesive bandage (band-aid) with a beige pad in the center, placed diagonally. BROKEN OR SIGNIFICANTLY INFLAMED SKIN
Where it may interfere with the planned procedure.
Clipboard icon with a checklist and a checkmark badge, representing completed tasks. A NEW OR UNDISCLOSED MEDICAL ISSUE
That requires further assessment.
Capsule-shaped pill icon, half gray and half white with a black outline, viewed diagonally in a simple graphic. A SIGNIFICANT CHANGE IN MEDICATION
Particularly where bleeding, healing or procedural suitability may be affected.
Yellow face emoji looking ill with a thermometer in its mouth, indicating fever or sickness. ACUTE ILLNESS
Where proceeding would be inappropriate.
Generic user profile icon (silhouette of a person) A DONOR AREA THAT IS NOT SUITABLE ON THE DAY
Final suitability still needs to be confirmed.
Chat message icon: two overlapping speech bubbles indicating messaging functionality EXPECTATIONS THAT HAVE CHANGED
Consent is not a form signed once and then forgotten.
If the treatment you now expect is different from the treatment that was discussed, the plan needs to be revisited.

YOUR PRE-TREATMENT CHECKLIST

Before your appointment, make sure you've completed the following checklist.

    I have disclosed my medical historyI have provided an up-to-date medication and supplement listI have told the clinic about previous filler, fat transfer, surgery or other relevant facial treatmentsI have disclosed smoking and nicotine useI have told the clinic about significant or ongoing weight changeI am not hiding an infection, illness or skin problem because I do not want my appointment cancelledI have not stopped prescribed medication without appropriate adviceI understand that the procedure involves both a donor site and facial treatment siteI have planned for swelling and bruisingI do not have an important event immediately after treatmentI know how I am getting home

    Bring any questions to your consultation.
    If anything changes before your appointment, please let the clinic know.
    One rule matters more than the rest: if something has changed since your consultation, tell us before treatment.

    ONE WEEK BEFORE YOUR APPOINTMENT

    Clipboard icon with a checklist and a checkmark badge, representing completed tasks.
    7 DAYS BEFORE
    Review medication, supplements, health changes and recovery plans.
    No alcohol permitted: bottle and wine glass shown inside a prohibitory circle
    48 HOURS BEFORE
    Avoid unnecessary skin irritation and follow your individual alcohol instructions.
    Line drawing of a button-down shirt with a plate containing a fork, knife, and spoon overlapping the lower-left area.
    THE DAY BEFORE
    Eat normally, stay hydrated and prepare comfortable clothing.
    Hospital building icon with a cross on the roof, central entrance, and side wings.
    TREATMENT DAY
    Arrive well, allow enough time and tell us if anything has changed.

    ONE IMPORTANT RULE

    IF SOMETHING HAS CHANGED, TELL US.
    A new medication.
    An infection.
    Antibiotics.
    A skin flare.
    A dental problem.
    A change in health.
    A significant change in weight.
    Something you forgot to mention at consultation.
    We would rather reassess the plan than discover important information halfway through the procedure.

    PREPARING FOR YOUR SEFFILLER TREATMENT

    Your preparation may be adjusted according to your medical history, medication, donor area and treatment plan.
    When What to do Important
    2 to 4 weeks before
    Tell us about any changes in your health, medication, allergies, smoking or nicotine use, and any significant or ongoing weight loss.
    Also disclose previous filler, permanent filler, biostimulators, threads, facial fat transfer, surgery or complications in the areas being assessed.
    7 days before
    Review all prescription medicines, over-the-counter medicines, vitamins, supplements and herbal products with the clinic.
    Do not stop prescribed medication unless the clinician responsible for that medication has specifically advised you to do so.
    During the week before
    Eat normally, keep normally hydrated and plan for possible swelling and bruising.
    Avoid crash dieting, fasting or deliberately changing your weight for the procedure.
    If anything changes
    Contact us if you become unwell, develop a fever, infection, rash, broken skin or significant inflammation, start antibiotics or begin a new medication.
    Treatment may need to be postponed. It is better to move an appointment than proceed when something important has changed.
    48 hours before
    Follow the alcohol instructions given for your procedure and avoid unnecessary irritation of the planned donor and facial treatment areas.
    Avoid aggressive exfoliation, home microneedling and other invasive treatments close to the procedure.
    The day before
    Eat normally, stay hydrated and prepare comfortable, practical clothing.
    Choose clothing that allows access to the planned donor area and does not fit tightly over it.
    Treatment day
    Arrive well, with clean skin where practical, and bring an up-to-date medication list if anything has changed.
    Unless you have specifically been told otherwise, do not arrive after unnecessary fasting or dehydrated.
    Before leaving home
    Make sure you have allowed enough time for the appointment and planned for your journey home and early recovery.
    Do not schedule treatment immediately before an important event, major photographs or essential travel.

    BEFORE YOUR APPOINTMENT, PLEASE TELL US IF…

    Health and medication Previous treatment Lifestyle and body changes
    You take medication or supplements that may affect bleeding or healing
    You have had filler in the areas being assessed
    You smoke, vape nicotine or use other nicotine products
    You are taking anticoagulant or antiplatelet medication
    You have had permanent or non-resorbable filler
    You are actively losing significant weight
    You take prescribed steroids or immunosuppressive treatment
    You have had a biostimulator, threads or previous fat transfer
    You are using weight-management medication
    You have started antibiotics or a new medication
    You have had facial surgery or a previous complication
    You are planning substantial further weight loss
    You have an infection, acute illness or significant skin problem
    You have had a recent procedure in the planned treatment area
    Your health or circumstances have changed since consultation
    Do not stop prescribed medication because of information on this page. Any change to prescribed treatment should be discussed with the clinician responsible for that medication.

    AFTERCARE FOLLOWING SEFFILLER

    Your aftercare may be adjusted according to the donor area, facial areas treated and how you are recovering. The instructions given to you after your procedure take priority over general website guidance.
    When Donor area Treated facial areas What to avoid
    First 24 hours
    Keep the dressing in place as instructed. A small amount of spotting may occur.
    Expect swelling, fullness, tenderness and possible early bruising.
    Pressing, rubbing or massaging the treated areas unless specifically advised.
    Days 1 to 3
    Bruising, tenderness and swelling may become more noticeable. Follow your dressing and washing instructions.
    Swelling and bruising may increase before they begin to settle. Temporary unevenness or asymmetry can occur.
    Strenuous exercise, unnecessary heat and pressure on treated areas.
    Days 4 to 7
    The area may still feel tender, firm or bruised.
    Early swelling should begin to evolve, but you may still look noticeably different from usual.
    Aggressive skincare, facial massage and unapproved cosmetic procedures.
    Weeks 2 to 6
    Tenderness and bruising should continue to improve.
    The face continues to settle. It may look less full than it did immediately after treatment.
    Judging the final result too early.
    Following months
    The donor area should continue to settle.
    The longer-term result becomes more meaningful to assess.

    PRACTICAL AFTERCARE

    Activity General guidance
    Touching the face
    Avoid unnecessary pressure, rubbing or massage of treated areas during early recovery unless specifically instructed otherwise.
    Sleeping
    You may be advised to sleep on your back initially and avoid direct pressure on treated facial areas. Your advice may vary according to the areas treated.
    Washing and showering
    Follow the instructions given for your donor-site dressing and skin entry points. Do not soak or unnecessarily disturb the area before you have been advised it is appropriate to do so.
    Makeup
    Wait until the skin entry points are appropriately healed and follow the timing given after your procedure. Do not apply makeup over broken or weeping skin.
    Skincare
    Keep skincare simple during early recovery. Avoid retinoids, strong acids, scrubs, home microneedling and other irritating products until advised to restart them.
    Exercise
    Avoid strenuous exercise during the early recovery period. Return gradually according to swelling, bruising, donor-site recovery and the advice given to you.
    Alcohol
    Avoid alcohol during the immediate recovery period according to your individual aftercare instructions, as it may worsen bruising or swelling in some patients.
    Heat
    Avoid saunas, steam rooms, very hot baths and intense heat exposure during early recovery.
    Swimming
    Wait until the donor and treatment entry points have healed appropriately and you have been advised it is suitable to return.
    Facials and massage
    Do not book facial massage, lymphatic massage of the treated face or other hands-on facial treatments until the area has settled and timing has been discussed.
    Other injectables
    Do not arrange filler, biostimulators, PRP, PRF or other injectable procedures in or around treated areas without discussing timing first.
    Energy-based treatments
    Lasers, radiofrequency, ultrasound-based treatments, microneedling and other device procedures should be timed individually. There is no sensible universal interval for every treatment.
    Travel and flying
    Discuss planned travel before treatment, particularly where it may limit access to follow-up or assessment if a concern develops.

    WHAT MAY BE EXPECTED, AND WHEN SHOULD YOU CONTACT US?

    Often seen during early recovery Contact the clinic promptly
    Swelling
    Pain that is severe, increasing or significantly different from what was explained
    Bruising
    Rapidly worsening or unusual swelling
    Tenderness
    Increasing redness, heat or spreading inflammation
    Temporary fullness
    Pus, discharge or other signs of possible infection
    Temporary firmness
    Persistent or significant bleeding
    Temporary unevenness
    Concerning skin colour change
    Asymmetry while swelling settles
    Blistering, skin breakdown or a wound that is worsening
    Donor-site discomfort
    Fever or feeling systemically unwell
    A small amount of spotting on the donor dressing
    Any symptom that is severe, rapidly changing or causing significant concern
    Do not wait for a routine review if you are concerned that something is wrong. Contact the clinic promptly for assessment.

    AFTERCARE CHECKLIST

      I understand how to care for the donor-site dressingI know that swelling and bruising may change during the first few daysI will not massage or repeatedly press the treated areas unless instructedI will avoid strenuous exercise during early recoveryI will keep skincare simple until the skin has recoveredI will not arrange other facial treatments without checking the timingI know how to contact the clinic if I am concernedI understand which symptoms require prompt or urgent assessmentI will not judge the final result during the early swelling phase

      The key rule is simple: protect the treated areas, look after the donor site, and report concerns early rather than trying to diagnose them through Google at 2 am.

      HOW DOES SEFFILLER COMPARE WITH OTHER TREATMENTS?

      SEFFILLER Nanofat Microfat / Traditional Facial Fat Transfer Dermal Filler PRF EZ Gel Biostimulators
      What is used?
      The patient’s own prepared microfragmented adipose tissue
      The patient’s own adipose tissue after further mechanical processing into a much finer preparation
      The patient’s own adipose tissue, prepared according to the fat-grafting technique used
      A manufactured injectable gel, most commonly hyaluronic acid
      A preparation made from the patient’s own blood
      An injectable product designed to produce a gradual tissue response
      Where does it come from?
      A small superficial fat harvest
      A fat harvest from a suitable donor area
      A fat harvest, often involving a larger-volume procedure
      Manufactured product
      A blood sample
      Manufactured product
      Requires a donor area?
      Yes
      Yes
      Yes
      No
      No
      No
      Requires a blood draw?
      No
      No
      No
      No
      Yes
      No
      Main treatment role
      Selected soft-tissue volume loss, with potential effects on aspects of tissue quality
      Primarily used for skin and tissue-quality indications rather than meaningful structural volume
      Volume restoration, which may range from targeted correction to broader facial volumisation
      Precise and immediately measurable volume, contour or structural correction
      Temporary soft-tissue support and blood-derived biological signalling
      Gradual improvement in selected aspects of tissue structure and quality
      Designed to add meaningful volume?
      Potentially, in selected areas
      Usually not its main purpose
      Yes
      Yes
      Limited and temporary
      Depends on the product, but generally not used like a conventional volumising filler
      Uses the patient’s own tissue?
      Yes
      Yes
      Yes
      No
      Uses the patient’s own blood
      No
      How is the material prepared?
      Small-volume guided harvest, washing and preparation according to the SEFFILLER protocol
      Further mechanical emulsification and processing of harvested fat
      Varies considerably according to the harvesting and processing technique
      Supplied ready for clinical use
      Blood is centrifuged and then processed into a gel preparation
      Supplied as a manufactured injectable product
      Immediate result?
      Early fullness is visible, but includes swelling and is not the final result
      Early appearance may be affected by swelling
      Early volume is visible but does not predict the final settled result
      Usually, although swelling can temporarily alter the appearance
      Yes, but the gel gradually changes over time
      Usually not the main objective; results develop gradually
      How predictable is the final volume?
      Variable because tissue persistence differs between patients
      Not primarily intended for predictable structural volume
      Variable because graft persistence differs
      Generally more immediately measurable
      Limited and temporary
      Not designed for precise immediate volumetric correction
      Can the result be precisely measured at treatment?
      Less precisely
      Not in the same way as filler
      Less precisely
      More precisely
      Limited
      No
      Reversible?
      No simple dissolving treatment
      No simple dissolving treatment
      No simple dissolving treatment
      HA filler can usually be dissolved with hyaluronidase
      No dissolving treatment, but the effect is temporary
      No simple reversal
      How quickly do results develop?
      The result evolves over weeks and months
      Changes develop as the area recovers
      The result evolves as swelling settles and transferred tissue stabilises
      Usually visible immediately, then settles
      Early correction is visible but changes as the preparation is resorbed
      Gradually over weeks to months
      How long can results last?
      Variable. Persisting transferred tissue may contribute to a longer-term result
      Duration of visible tissue-quality change varies
      Persisting grafted tissue may remain long term, but the visible result continues to change with ageing and weight
      Product, area and patient dependent
      Generally shorter-lived than established fat grafting or many fillers
      Product and patient dependent
      Is all transferred material expected to remain?
      No
      Not applicable in the same volumetric sense
      No
      The product gradually degrades over time
      The preparation gradually changes and is resorbed
      The injected product and resulting tissue response evolve over time
      Downtime
      Swelling and bruising may occur at both donor and treated areas
      Donor-site and treatment-area recovery
      Usually more involved, depending on the extent of harvest and transfer
      Usually less than fat-transfer procedures
      Usually limited, although swelling and bruising can occur
      Usually limited, although product-specific reactions can occur
      Main practical advantage
      Small-volume autologous tissue transfer without a conventional larger-volume fat-grafting procedure
      Very fine fat-derived preparation for selected superficial tissue concerns
      Greater potential for broader or more substantial autologous volume restoration
      Precision, immediate control and, with HA, reversibility
      Uses a blood-derived preparation without a fat harvest
      Gradual treatment approach without adding harvested fat
      Main practical limitation
      Requires a donor procedure and the degree of tissue persistence cannot be predicted exactly
      Not designed to provide the same structural volume as viable fat grafting
      More involved procedure with variable graft persistence
      Uses a manufactured product and has product- and area-specific risks
      Volume effect is limited and temporary
      Results are gradual and cannot be precisely sculpted like filler
      Best suited to every patient?
      No
      No
      No
      No
      No
      No
      This table is a guide, not a treatment hierarchy. SEFFILLER is not automatically better because it uses your own tissue. Filler is not automatically inferior because it is manufactured. Nanofat is not simply “better fat”, and a biostimulator is not a facelift in a syringe. The right option depends on what has actually changed, the degree of correction required, the predictability you want and the procedure you are willing to undergo.

      WHAT DOES THE EVIDENCE SHOW?

      SEFFILLER sits within the wider field of autologous facial fat transfer, but it also has published research on the SEFFI and Micro-SEFFI techniques specifically.
      The evidence is promising, particularly for facial volume restoration and reported changes in aspects of tissue quality.
      It is not perfect.
      Most of the published clinical evidence is based on case series, observational studies and retrospective data rather than multiple large randomised controlled trials.
      That matters.
      A treatment can have a credible biological rationale, published clinical experience and encouraging outcomes without every claim being definitively proven.

      THE EVIDENCE AT A GLANCE

      What has been studied? What the research suggests What it does not prove
      Facial volume loss
      SEFFI techniques have been used for selected areas of facial volume restoration
      That every patient will retain the same amount of transferred tissue
      Facial ageing
      Published clinical studies have reported improvements following treatment
      That SEFFILLER reverses ageing
      Periocular area
      The technique has been studied around the eyes and lid-cheek region
      That every dark circle, eye bag or under-eye concern is suitable for fat transfer
      Perioral area
      Micro-SEFFI has been studied for ageing changes around the mouth
      That every line around the mouth will improve
      Tissue composition
      Laboratory studies have examined the cellular, stromal and structural components of the harvested tissue
      That SEFFILLER is an isolated stem-cell treatment
      Skin and tissue quality
      Changes in aspects of tissue quality have been reported
      Guaranteed collagen production, skin regeneration or reversal of skin ageing
      Larger clinical experience
      A multicentre retrospective study reported experience across more than 2,000 procedures
      The same level of evidence as a large randomised controlled trial

      THE RESEARCH JOURNEY

      Silhouette of a compound microscope with a round cell specimen on the stage, illustrating microscopy.

      1. THE TISSUE

      What is actually being transferred?
      Laboratory research has examined the adipose, stromal and vascular components present within Micro-SEFFI preparations.
      Healthcare professional icon (doctor) with a stethoscope, and a vaccine syringe emblem on a black badge.

      2. THE TECHNIQUE

      Can superficial small-volume fat transfer be used in the face?
      Published clinical work has described the SEFFI approach for facial volume loss and ageing.
      Face inside a square frame icon, representing facial recognition or identity verification

      3. SPECIFIC FACIAL AREAS

      What happens around the eyes and mouth?
      Clinical studies have examined periocular and perioral treatment.
      Bar chart with four increasing bars showing growth from left to right on a baseline.

      4. LARGER CLINICAL EXPERIENCE

      What happens when the technique is used across larger numbers of patients?
      A multicentre retrospective study reported experience from 2,365 procedures.

      HOW STRONG IS THE EVIDENCE?

      Evidence type Available for SEFFI / Micro-SEFFI? What it can tell us
      Laboratory and tissue-characterisation research
      Yes
      Helps us understand what the harvested tissue contains
      Clinical case series
      Yes
      Shows how the technique has been used and what outcomes have been reported
      Prospective clinical studies
      Some published clinical work is available
      Can examine changes over time in treated patients
      Large retrospective clinical data
      Yes
      Provides useful information from a larger volume of real-world procedures
      Multiple large randomised controlled trials
      No established body of evidence
      This is why broad claims of proven superiority would be inappropriate
      Long-term head-to-head trials against every alternative
      No
      We cannot honestly claim that SEFFILLER is universally better than filler, PRF, nanofat or biostimulators

      WHAT WE CAN REASONABLY SAY

      SUPPORTED BY THE CURRENT EVIDENCE

      SEFFI techniques have been published for facial volume loss and ageing.
      The periocular and perioral regions have been studied.
      Micro-SEFFI preparations contain more than mature adipocytes alone.
      Published research has examined stromal and vascular components within the tissue.
      Changes in volume and aspects of tissue quality have been reported.
      A large retrospective multicentre series provides useful real-world clinical experience.

      WHAT WE WILL NOT CLAIM

      SEFFILLER permanently regenerates the face.
      It is a proven stem-cell treatment.
      All transferred fat survives.
      It creates a guaranteed amount of collagen.
      It is clinically proven to be better than dermal filler.
      It replaces a facelift.
      One treatment produces a permanent result.
      Every patient will experience improvement in skin quality.

      A LARGE STUDY IS NOT AUTOMATICALLY A STRONG STUDY

      The largest published SEFFI series included 2,365 procedures.
      A large number of procedures can help us understand:
      how a technique is being used in clinical practice
      which areas are being treated
      what complications have been reported
      patterns of real-world experience
      But the study was retrospective.
      That means it cannot answer every question that a well-designed randomised controlled trial could answer.
      Patient numbers matter. Study design matters too.
      We look at both.

      THE “STEM CELL” PROBLEM

      Fat-derived procedures are often marketed using the phrase stem-cell treatment.
      That is not how we describe SEFFILLER.
      The transferred adipose tissue contains a complex mixture of:
      mature adipocytes
      stromal components
      vascular-associated cells
      extracellular matrix
      different cell populations within the adipose tissue environment
      Researchers have studied adipose-derived stromal cell populations because of their potential signalling and tissue-supporting roles.
      But that is not the same as:
      isolating a purified stem-cell population
      or
      injecting a laboratory-expanded stem-cell medicine
      SEFFILLER transfers prepared adipose tissue.
      The science is already interesting. It does not need a more dramatic name.

      BIOLOGICAL PLAUSIBILITY VS CLINICAL PROOF

      BIOLOGICAL PLAUSIBILITY CLINICAL PROOF
      A mechanism could reasonably occur
      A meaningful outcome has been demonstrated in patients
      Often explored in laboratory research
      Requires appropriate clinical studies
      Helps explain how a treatment might work
      Tells us whether patients actually benefit
      Important
      Also important
      Not enough on its own
      Should still be interpreted according to study quality
      A mechanism can be fascinating under a microscope and still fail to produce a meaningful cosmetic result. Good evidence asks both questions: what may be happening biologically, and what can patients actually expect to see?

      OUR APPROACH TO THE EVIDENCE

      We do not dismiss SEFFILLER because the evidence is not perfect.
      Very few procedures in aesthetic medicine have a flawless evidence base.
      We also do not inflate the science because the treatment is new, autologous or biologically interesting.
      Our approach is to separate:
      Shield icon with a checkmark indicating security or verification status

      WHAT IS ESTABLISHED

      The procedure transfers the patient’s own prepared adipose tissue.
      Clipboard with a list and a magnifying glass featuring an eye, symbolizing document review or inspection.

      WHAT HAS BEEN OBSERVED

      Published studies have reported clinical changes following SEFFI techniques.
      Silhouette of a compound microscope with a round cell specimen on the stage, illustrating microscopy.

      WHAT IS BIOLOGICALLY PLAUSIBLE

      The transferred tissue contains cellular and structural components that may interact with the surrounding tissue environment.
      Help icon: question mark inside a circle, indicating information or assistance

      WHAT REMAINS UNCERTAIN

      The exact contribution of each component, the degree of tissue persistence in an individual patient and the extent of any visible tissue-quality change.

      RISKS AND POSSIBLE COMPLICATIONS

      SEFFILLER involves harvesting adipose tissue from one area and transferring it to another. This means risks may arise at the donor area, the treated area, or from the procedure more generally.
      Most side effects are expected to improve as healing progresses. Some complications can last longer, require further treatment or, rarely, be serious.

      RISKS AT A GLANCE

      Possible issue Where it may occur What you should know
      Pain or tenderness
      Donor or treated area
      Common during early recovery and usually improves with time
      Swelling
      Donor or treated area
      Expected to some degree. It may be uneven and can temporarily alter the appearance
      Bruising
      Donor or treated area
      Common and may become more noticeable during the first few days
      Bleeding or spotting
      Particularly the donor entry site
      A small amount may occur early on. Persistent or significant bleeding requires assessment
      Redness
      Donor or treated area
      Mild early redness may occur. Increasing redness, heat or pain requires review
      Temporary firmness
      Donor or treated area
      Tissue may feel different while swelling and healing settle
      Numbness or altered sensation
      Donor or treated area
      Usually temporary, but sensory changes can occasionally persist
      Asymmetry
      Treated area
      Early asymmetry may reflect swelling. Longer-lasting asymmetry may relate to anatomy or uneven tissue persistence
      Under-correction
      Treated area
      Less volume may persist than hoped for
      Over-correction
      Treated area
      Excessive or unwanted fullness may occur and is not simply reversible with a dissolving enzyme
      Irregularity or contour change
      Donor or treated area
      Lumps, depressions, unevenness or visible contour differences can occur
      Palpable nodules or firmness
      Treated area
      Some areas may become firm or palpable and may require assessment
      Fat necrosis
      Treated area
      A portion of transferred fat may not survive and can form a firm area, nodule or cystic change
      Oil cyst formation
      Treated area
      Breakdown of non-surviving fat may occasionally produce an oil-containing cyst
      Infection
      Donor or treated area
      Uncommon but may require antibiotics, drainage or other treatment
      Scarring
      Entry points
      Entry points are small, but any break in the skin can leave a scar or pigment change
      Pigment change
      Donor or treated area
      Post-inflammatory darkening or lightening can occur, particularly after bruising or inflammation
      Prolonged swelling
      Treated area
      Swelling may last longer than expected, particularly in anatomically sensitive areas
      Unsatisfactory cosmetic result
      Treated area
      The final result may differ from what was hoped for, even when the procedure has been performed as planned
      Need for further treatment
      Donor or treated area
      Additional treatment, correction or specialist assessment may sometimes be required
      The final amount of tissue that persists cannot be predicted exactly. Too little, too much, unevenness or asymmetry are therefore important considerations before treatment, not merely technical footnotes.

      RISKS SPECIFIC TO FAT TRANSFER

      Fat-transfer consideration What it means
      Variable tissue persistence
      Not all transferred tissue can be expected to remain. The degree of correction may reduce as swelling settles and non-persisting tissue is resorbed
      Uneven persistence
      Tissue may not persist identically in every area, which can contribute to asymmetry or irregularity
      Fat necrosis
      Fat that does not survive may break down and form a firm or tender area
      Oil cysts
      Breakdown of fat can occasionally result in cystic collections
      Calcification
      Areas of fat necrosis can occasionally develop calcification over time
      Over-correction
      Persisting tissue cannot be dissolved in the same way as hyaluronic acid filler
      Under-correction
      The final result may be subtler than hoped for
      Response to weight change
      Persisting adipose tissue remains biologically responsive and the appearance may change with significant weight gain or loss
      Need for revision or further treatment
      Further assessment or treatment may occasionally be needed if the result is insufficient, excessive, uneven or complicated

      THE DONOR AREA HAS ITS OWN RISKS

      Patients naturally focus on the face.
      The donor area should not be forgotten.
      Possible donor-site issue What you should know
      Bruising and tenderness
      Common during early recovery
      Swelling
      May occur and can temporarily change the feel or appearance of the area
      Bleeding or fluid leakage
      A small amount may occur early after the procedure
      Temporary firmness
      The tissue may feel different while healing
      Contour irregularity
      A depression, unevenness or local contour change can occur
      Altered sensation
      Temporary numbness or sensitivity may occur
      Infection
      Requires prompt assessment and treatment
      Scarring or pigment change
      The entry point is small but can still leave a visible mark
      Persistent discomfort
      Uncommon, but symptoms that do not improve should be assessed
      SEFFILLER is not a body-contouring treatment.
      The aim of the harvest is to collect tissue for transfer, not to create visible slimming at the donor site.

      RARE BUT SERIOUS COMPLICATIONS

      Any procedure involving instruments and material being placed into facial tissue carries the possibility of uncommon but potentially serious complications.
      These may include:
      Serious complication Why it matters
      Severe infection
      May require urgent medical treatment, antibiotics, drainage or hospital care
      Significant tissue injury
      Damage to surrounding structures can have lasting consequences
      Vascular injury or intravascular fat entry
      Accidental entry of fat into a blood vessel can cause serious tissue injury and, in rare circumstances, severe neurological or visual complications
      Visual disturbance or vision loss
      Rare but potentially devastating and requires immediate emergency assessment
      Neurological complications
      Rare vascular events involving the brain can be life-threatening or cause permanent disability
      Severe allergic reaction
      May occur in response to medicines or other materials used during the procedure
      Thromboembolic or other serious medical events
      Rare complications may require urgent hospital treatment
      The purpose of including these risks is not to suggest that they are common.
      It is to be clear that “using your own fat” does not mean “risk-free”.
      Autologous describes the source of the tissue. It does not remove the procedural risks of harvesting and transferring it.

      WHEN TO CONTACT THE CLINIC

      Contact the clinic promptly if you notice
      Pain that is increasing rather than improving
      Rapidly worsening or unusual swelling
      Increasing redness, heat or spreading inflammation
      Pus, discharge or signs of possible infection
      Persistent or significant bleeding
      A concerning change in skin colour
      Blistering, skin breakdown or a worsening wound
      A new or enlarging painful lump
      Fever or feeling systemically unwell
      Any symptom that is severe, rapidly changing or significantly different from what was explained

      WHEN TO SEEK URGENT MEDICAL HELP

      Seek urgent medical attention for
      Sudden visual disturbance, loss of vision or severe eye symptoms
      New weakness, difficulty speaking, confusion or other sudden neurological symptoms
      Difficulty breathing or severe allergic symptoms
      Chest pain, collapse or sudden severe illness
      Rapidly progressive severe symptoms
      If you believe you are experiencing a medical emergency, seek urgent medical assistance rather than waiting for a routine clinic response.

      RISK IS PERSONAL

      The chance and significance of a complication are not identical for every patient.
      Risk may be influenced by:
      the area being treated
      previous filler, fat transfer or surgery
      medical conditions
      medication
      smoking and nicotine use
      tissue quality
      anatomy
      healing response
      the donor area
      the amount and pattern of tissue transfer
      This is why a list of risks on a website is not a substitute for individual assessment and informed consent.

      BEFORE YOU DECIDE

      A reasonable decision about SEFFILLER means understanding that…
      The procedure involves both a donor area and a treatment area
      Swelling, bruising and temporary unevenness are part of the recovery
      Not all transferred tissue can be expected to persist
      The final amount of correction cannot be predicted exactly
      Fat cannot simply be dissolved like hyaluronic acid filler
      Further treatment or correction may occasionally be required
      Rare but serious complications are possible
      Choosing not to have treatment is always an option
      The aim of consent is not to make a procedure sound frightening or harmless. It is to make the decision informed.

      Clinical Before & After Results

      Pricing

      Pricing is confirmed at consultation depending on the areas treated and the complexity of your individual plan. If one session is appropriate, we’ll say that. If a course makes more sense, we’ll explain why.

      A Note on Transparency

      PRF EZ Gel Biofiller is frequently marketed in ways that overstate what it does. Claims of long-lasting structural volume, permanent regeneration, or results comparable to dermal fillers aren’t supported by the current evidence. The published literature on plasma gel treatments is still relatively limited, and most studies are small and early in their design.

      What we can say with reasonable confidence: PRF Biofiller improves subtle hollowing and early volume loss in suitable patients, delivers some regenerative stimulus through the PRF component, and does so without synthetic material. Results are real but modest, and maintenance is part of the treatment.

      We think patients deserve to know that before they book. The consultation is where we work out whether this treatment makes sense for you, and if something else would work better, we’ll recommend that instead.

      Our Treatment Specialists

      CACI Rejuvamed

      Dr. Hansel Misquitta

      Founder | Dr. Hans Clinics

      MBBS | MSc Plastic & Reconstructive Surgery (UCL) | PGDip Bioethics (UNESCO Chair)

      View Profile
      Kirsty Jamieson

      Kirsty Jamieson

      skin therapist

      With over 20 years in the Aesthetics, Beauty, Wellness and holistic space

      View Profile

      Dr. Vincent Wong

      Cosmetic Doctor

      GMC Registered

      View Profile

      FAQ's - ABOUT SEFFILLER AND FACIAL FAT TRANSFER

      ABOUT THE TREATMENT

      What is SEFFILLER?

      SEFFILLER is a small-volume autologous fat transfer procedure. A small amount of superficial adipose tissue is collected from a suitable donor area, prepared according to the SEFFILLER protocol and transferred to selected areas in the same patient.

      The procedure uses your own tissue rather than a manufactured dermal filler.

      SEFFILLER is based on the SEFFI technique, which stands for Superficial Enhanced Fluid Fat Injection

      SEFFILLER is a form of facial fat transfer, but not all facial fat transfer is SEFFILLER.

      “Facial fat transfer” is a broad term covering many different methods of:

      • harvesting fat
      • processing it
      • selecting particle size
      • transferring it
      • choosing the amount and treatment depth

      SEFFILLER is a specific system and protocol designed around the collection and preparation of relatively small amounts of superficial adipose tissue.

      This is different from larger-volume fat grafting procedures that may involve conventional liposuction and broader facial volumisation.

      No.

      The terms are often mixed together online, but they should not be used interchangeably.

      Nanofat generally refers to harvested adipose tissue that has undergone further mechanical processing and emulsification to create a very fine preparation. It is mainly discussed for superficial tissue and skin-quality indications rather than predictable structural volume.

      SEFFILLER uses prepared microfragmented adipose tissue and may be considered where selected volume restoration forms part of the treatment goal.

      The exact harvesting and processing methods matter. Calling every finely prepared fat-transfer procedure “nanofat” is inaccurate.

      Not exactly.

      Microfat is a broader term used for small-particle fat grafting techniques intended to preserve viable adipose tissue for volume restoration.

      SEFFILLER is a specific device-assisted system and protocol for small-volume harvesting and preparation of adipose tissue.

      There is overlap within the wider field of small-volume facial fat grafting, but the terms should not simply be treated as brand synonyms.

      No. We do not market it as one.

      Adipose tissue contains a complex mixture of mature fat cells, extracellular matrix and stromal and vascular-associated cell populations.

      Some of these populations are scientifically interesting because of their potential roles in cellular signalling and tissue response.

      That does not make the procedure equivalent to:

      • isolated stem-cell therapy
      • laboratory-expanded cell treatment
      • a purified stem-cell injection

      SEFFILLER transfers prepared adipose tissue from one area of the patient to another.

      The science is interesting enough without renaming the procedure.

      The word regenerative is used very loosely in aesthetic medicine.

      Fat-derived procedures are being studied for biological effects beyond simple volume replacement, including interactions involving cellular signalling, vascular responses and the extracellular matrix.

      However, the term should not be used to promise that SEFFILLER:

      • regenerates a new face
      • reverses ageing
      • replaces damaged tissue with new tissue
      • guarantees new collagen
      • acts as a proven stem-cell therapy

      We prefer to describe the actual procedure and the evidence rather than rely on a fashionable label.

      RESULTS AND LONGEVITY

      How long does SEFFILLER last?

      There is no single expiry date.

      Early fullness includes swelling and fluid and should not be confused with the final result.

      Over time:

      1. swelling settles
      2. the treated area changes
      3. some transferred tissue may not persist
      4. tissue that does persist may contribute to the longer-term result

      The visible outcome can continue to change with:

      • ageing
      • weight change
      • health
      • lifestyle
      • changes in surrounding facial tissues

      For this reason, we do not promise a fixed duration or describe SEFFILLER as “permanent filler”.

      This question needs a more careful answer than yes or no.

      Transferred adipose tissue that successfully persists may remain long term. However, that does not mean:

      • all transferred fat survives
      • the immediate result is permanent
      • the face stops ageing
      • body weight never affects the result
      • every patient retains the same amount

      The more accurate description is that persisting transferred tissue may contribute to a longer-term result, while the face continues to change naturally over time.

      There is no honest universal percentage.

      Fat graft persistence varies according to:

      • the harvesting technique
      • tissue preparation
      • tissue handling
      • recipient area
      • placement technique
      • individual biology
      • smoking and nicotine exposure
      • general health
      • weight change

      Survival figures from one type of fat grafting should not automatically be copied and pasted onto another technique.

      We therefore do not promise a fixed percentage of fat survival.

      The appearance changes gradually.

      Immediately after treatment, the area may look fuller because of transferred tissue, swelling and fluid.

      During the following weeks, swelling reduces and the appearance continues to evolve.

      A more meaningful assessment is generally made after the early recovery and settling period rather than immediately after treatment.

      The exact review schedule depends on the areas treated and your individual recovery.

      Because the appearance immediately after treatment was never the final result.

      Early fullness can include:

      • swelling
      • local fluid
      • tissue response to the procedure
      • the transferred tissue itself

      As these early effects settle, the face may look less full.

      Some transferred tissue may also not persist.

      This is an expected part of understanding fat transfer and does not automatically mean the procedure has failed.

      Possibly, but repeat treatment should not be automatic.

      Some patients may be satisfied after one procedure. Others may consider further treatment depending on:

      • the starting anatomy
      • the area treated
      • the degree of correction required
      • how the initial treatment settles
      • the amount of visible correction that remains
      • whether further treatment is actually worthwhile

      The first result should be given appropriate time to settle before deciding what comes next.

      TREATMENT AREAS

      Can SEFFILLER be used under the eyes?

      It may be considered in selected patients where genuine soft-tissue deficiency contributes to:

      • under-eye hollowing
      • a pronounced lid-cheek transition
      • selected periocular volume loss

      It is not suitable for every tired-looking under-eye.

      The appearance may instead be caused by:

      • prominent eye bags
      • festoons
      • malar oedema
      • pigmentation
      • visible vessels
      • skin laxity
      • skeletal anatomy

      Adding volume to the wrong under-eye can make it look heavier.

      The cause matters more than the label “dark circles”.

      Neither is universally better.

      Hyaluronic acid filler can offer more precise, immediately measurable correction and can usually be dissolved if necessary.

      Fat transfer uses the patient’s own tissue but requires a donor procedure, involves more recovery and has less predictable final volume persistence.

      Some patients are better suited to filler.

      Some may be considered for fat transfer.

      Some should have neither.

      Anatomy decides.

      Potentially.

      Temple hollowing may relate to:

      • natural anatomy
      • ageing
      • weight loss
      • changes in soft tissue
      • skeletal structure

      Where soft-tissue volume loss is an important part of the concern, fat transfer may be one option to discuss.

      The temple is anatomically complex, and treatment planning must consider the degree of hollowing, previous procedures and the surrounding facial proportions.

      It may be considered for selected cheek and midface volume loss.

      However, a flatter or older-looking midface is not always simply missing volume.

      The concern may also involve:

      • tissue descent
      • skin laxity
      • skeletal change
      • changes in facial proportions

      Fat transfer adds tissue. It does not reproduce a surgical lift.

      In selected patients, fat transfer may be considered where soft-tissue deficiency contributes to the appearance.

      However, nasolabial folds are influenced by facial structure, movement, cheek anatomy, tissue position and skin quality.

      The goal should not automatically be to erase the fold.

      Everyone has nasolabial folds. A completely flat face is not the biological definition of youth.

      Changes in aspects of tissue quality have been reported and studied following fat-derived procedures.

      The biological interest comes from the fact that adipose tissue contains more than mature fat cells. It also contains extracellular matrix and a mixed stromal and vascular tissue environment.

      However, visible improvement varies.

      SEFFILLER should not be expected to:

      • erase pores
      • remove scars
      • eliminate wrinkles
      • reverse ageing
      • guarantee collagen production

      If skin quality is the main concern, another treatment may be more appropriate.

      SUITABILITY

      Can very slim people have SEFFILLER?

      Possibly.

      SEFFILLER requires a relatively small amount of adipose tissue compared with larger-volume fat grafting, but a suitable donor area is still required.

      Potential donor areas may include the:

      • abdomen
      • hip or flank region
      • outer thigh region

      Being slim does not automatically exclude treatment.

      Equally, having a small amount of body fat somewhere does not automatically make it an appropriate donor site.

      Suitability must be assessed individually.

      A suitable area of superficial subcutaneous adipose tissue is selected.

      Common potential donor areas include the:

      • abdomen
      • hips or flank region
      • outer thigh region

      The donor area is chosen according to anatomy and suitability for the procedure.

      It is not chosen according to where a patient most wants to lose weight.

      SEFFILLER is not a body-contouring treatment.

      No meaningful body-contouring result should be expected.

      Only a relatively small amount of tissue is collected for the planned transfer.

      The purpose is to obtain tissue for treatment, not to slim or reshape the abdomen, hips or thighs.

      Possibly.

      Previous filler does not automatically rule out fat transfer, but the history matters.

      We need to know:

      • which product was used
      • where it was placed
      • when it was injected
      • how much was used
      • whether it was dissolved
      • whether swelling or complications occurred

      Old filler may still be relevant even when it was injected years ago.

      Previous treatment records or further assessment may sometimes be needed before a plan is made.

      Not automatically.

      The answer depends on:

      • the type of filler
      • where it was placed
      • whether it is still present
      • whether it is causing a problem
      • the area being considered for fat transfer

      Dissolving filler unnecessarily is not a ritual that every patient must complete before another treatment.

      The area needs to be assessed first.

      WEIGHT LOSS AND GLP-1 MEDICATION

      Can I have facial fat transfer after weight loss?

      Potentially.

      Weight loss can produce:

      • temple hollowing
      • flatter cheeks
      • a more pronounced lid-cheek junction
      • general facial depletion

      However, some patients develop mainly:

      • loose skin
      • tissue descent
      • prominent folds

      Fat transfer is more relevant where loss of soft-tissue volume is a meaningful part of the concern.

      If substantial weight loss is still continuing, timing should be considered carefully.

      Taking a weight-management medication does not, by itself, answer whether you are suitable for facial fat transfer.

      The assessment needs to consider:

      • why you take the medication
      • your current health
      • how quickly your weight is changing
      • whether substantial further weight loss is expected
      • nutritional status
      • other medication
      • the planned procedure

      Do not stop prescribed medication in preparation for treatment unless the clinician responsible for that medication has specifically advised you to do so.

      Treatment timing is individual.

      Sometimes.

      If you are still losing a substantial amount of weight, the face may still be changing.

      Waiting until the pattern is clearer may make treatment planning more sensible.

      This does not mean every patient must reach a perfect target weight or remain exactly the same weight forever.

      The question is whether enough stability exists to plan treatment around the face you are likely to have.

      Further weight loss may change:

      • the treated face
      • untreated facial areas
      • overall facial proportions
      • the donor area

      Persisting adipose tissue remains biologically responsive.

      Significant weight change can therefore alter the appearance over time.

      Persisting adipose tissue may respond to wider changes in body composition.

      This does not mean the treated area will necessarily enlarge dramatically.

      It means that transferred living adipose tissue remains part of a body that can change.

      Large weight changes may alter facial proportions.

      THE PROCEDURE AND RECOVERY

      Is SEFFILLER painful?

      The standard procedure uses local anaesthesia.

      Patients may still experience:

      • the initial anaesthetic injections
      • pressure
      • movement
      • pulling
      • unusual sensations during tissue harvesting

      Tenderness may occur afterwards at both the donor and treated areas.

      We do not describe the procedure as painless because comfort varies between patients.

      It involves harvesting adipose tissue, but it should not be confused with conventional body-contouring liposuction.

      SEFFILLER is designed around a small-volume, syringe-based tissue harvest using its dedicated system.

      Traditional liposuction generally involves a larger-volume procedure intended to alter body contour.

      The purpose and scale are different.

      Downtime varies.

      Possible early effects include:

      • swelling
      • bruising
      • tenderness
      • temporary firmness
      • temporary unevenness
      • donor-site discomfort

      Some patients may feel physically able to work before they feel ready for photographs, filming or important social events.

      If you need to look completely normal by a fixed date, plan conservatively.

      Possibly, depending on:

      • the areas treated
      • your work
      • your recovery
      • how visible swelling or bruising is acceptable to you

      Working from home is different from filming in high definition.

      Your recovery plan should reflect your actual life.

      Strenuous exercise should be avoided during the early recovery period.

      The timing of return depends on:

      • swelling
      • bruising
      • donor-site recovery
      • the extent of treatment
      • individual healing

      You will be given specific instructions after your procedure.

      Travel should be discussed before treatment.

      The main considerations include:

      • access to follow-up
      • the ability to return for assessment
      • swelling and comfort
      • the length and nature of the journey
      • individual medical risk factors

      We do not use one universal flying rule for every patient and every procedure.

      SAFETY AND DECISION-MAKING

      Is SEFFILLER safer because it uses my own fat?

      Using your own tissue avoids some issues associated with introducing a manufactured volumising material.

      It does not make the procedure risk-free.

      Possible risks include:

      • infection
      • bleeding
      • contour irregularity
      • asymmetry
      • under-correction
      • over-correction
      • fat necrosis
      • oil cysts
      • donor-site problems
      • rare but serious vascular complications

      “Your own tissue” describes the source of the material.

      It is not a safety guarantee.

      No.

      Transferred fat cannot be dissolved with hyaluronidase in the way hyaluronic acid filler usually can.

      This is an important difference.

      Possible management of an unwanted result depends on the actual problem and may be more complex.

      Patients who place a high value on reversibility should consider this carefully before choosing fat transfer.

      Not universally.

      SEFFILLER and dermal filler solve different problems in different ways.

      Dermal filler may offer:

      • greater immediate precision
      • measured product volume
      • less donor-site involvement
      • reversibility when hyaluronic acid is used

      SEFFILLER offers:

      • use of the patient’s own adipose tissue
      • a different biological and procedural approach
      • potential longer-term contribution from tissue that persists

      The better option depends on the anatomy, treatment goal, required precision, acceptable recovery and patient preference.

      They are very different treatments.

      PRF EZ Gel is prepared from the patient’s blood.

      SEFFILLER uses the patient’s adipose tissue.

      PRF EZ Gel does not require a fat donor site and its volumising effect is generally more temporary.

      SEFFILLER involves a more substantial procedure and variable tissue persistence.

      Neither is automatically better.

      They should not be treated as interchangeable.

      SEFFILLER transfers adipose tissue.

      Biostimulators use manufactured injectable products intended to produce a gradual tissue response.

      The choice depends on:

      • whether actual volume restoration is required
      • how precise the correction needs to be
      • whether a donor procedure is acceptable
      • the area being treated
      • the patient’s medical and treatment history
      • the risks and limitations the patient considers acceptable

      There is no single best treatment for every ageing face.

      The assessment should answer:

      1. What has actually changed?
      2. Is soft-tissue volume loss genuinely part of the problem?
      3. Would adding tissue improve the area?
      4. Is fat transfer the right way to do it?
      5. Is there a suitable donor area?
      6. Are the expected benefits worth the procedure and recovery?

      Sometimes the answer will be SEFFILLER.

      Sometimes another treatment will make more sense.

      Sometimes the most appropriate treatment is no treatment at all.

      Reviews

      Semih
      ★★★★★
      Before booking PRF EZ Gel for my under eyes, I had a lot of questions and concerns. Dr Hans took time to go through all of them properly and did not rush the consultation. She explained the treatment in a balanced way and set realistic expectations. The procedure itself was more comfortable than I imagined and the result looks very natural. My face looks more rested rather than noticeably treated, which was important to me.
      Elene Gelashvili
      ★★★★★
      I had a great experience with Dr. Hans. I wanted to do Ez gel under my eyes. She listened to my concerns and took her time to explain why it wouldn’t be suitable treatment for me. Instead we agreed to tighten my skin with Tixel - I had 3 sessions, very happy with the results.
      Rachael Epstein
      ★★★★★
      Absolutely the most knowledgeable and kindest doctor I’ve met. I’ve had injectables and PRF and soon tixel with her. She makes you feel so comfortable and confident. She will also say no and not just try to sell which is so important. She truly wants to improve the life of others which isn’t the case throughout the aesthetic industry (a lot of people try to exploit insecurities) and I used to work in it so I know! Thank you so much

      Treatment Location

      Quick Links
      Small-volume fat transfer using your own adipose tissue
      What Seffiller is
      How the Treatment Works
      What Can Seffiller Be Used For
      Who May Be Suitable For Seffiller
      Results And Timeline
      Your Seffiller Treatment Journey
      What Does The Evidence Show
      Clinic Before & After Results
      FAQ's

      INDICATIONS & EVIDENCE

      Condition Mechanism Key Evidence
      Telogen Effluvium / Stress Hair Loss
      Enhances growth factor signalling for anagen induction
      Choi et al., Int J Mol Sci 2021
      Seborrhoeic / Inflammatory Scalp
      Reduces cytokine activity and improves scalp barrier
      Kim et al., J Cosmet Dermatol 2020
      Postpartum Shedding / Hormonal Loss
      Supports microvascular regeneration
      Kang et al., Dermatol Ther 2019
      Adjunct Post-PRP or PRF
      Enhances fibroblast response
      Clinical consensus, 2022

      BOOK A SEFFILLER CONSULTATION IN LONDON

      Consultation does not commit you to treatment. Suitability is assessed individually, and treatment may be declined or an alternative approach recommended where appropriate.

      Book Consultation
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