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Your journey starts with a free initial consultation (in person or virtual) → followed by a tailored treatment plan.
Book a consultation at Dr Hans Clinics, London to see if Profhilo is right for you.
Profhilo – Skin Booster
Glow Beyond the Surface
From £325 - £650 per session
Experience the future of non-surgical rejuvenation with Profhilo – an advanced injectable moisturiser that delivers deep hydration and skin remodelling. Whether it’s your face, neck, or body, Profhilo works to restore natural elasticity, smoothness, and a youthful glow without adding volume.
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What Is Profhilo?
Profhilo is a unique injectable skin booster made of ultra-pure hyaluronic acid (HA). Unlike traditional dermal fillers that add volume, Profhilo spreads evenly under the skin to stimulate collagen, elastin, and hydration — restoring firmness and radiance without changing facial shape.
How Profhilo Works – The Molecular Biology
● Hyaluronic Acid Release: Profhilo contains 64mg of high- and low-molecular weight HA.
● Dual-Action Technology:
○ Low-MW HA → hydrates by binding water molecules, improving turgor and glow.
○ High-MW HA → acts as a scaffold, stimulating fibroblasts.
● Collagen & Elastin Production: HA fragments bind to CD44 receptors on fibroblasts and keratinocytes → trigger pathways that increase Type I & III collagen and tropoelastin.
● Bio-remodelling: Over 4 weeks, skin becomes firmer, tighter, and more elastic.
Think of Profhilo as “liquid scaffolding” — it doesn’t fill, it rebuilds.
● Dual-Action Technology:
○ Low-MW HA → hydrates by binding water molecules, improving turgor and glow.
○ High-MW HA → acts as a scaffold, stimulating fibroblasts.
● Collagen & Elastin Production: HA fragments bind to CD44 receptors on fibroblasts and keratinocytes → trigger pathways that increase Type I & III collagen and tropoelastin.
● Bio-remodelling: Over 4 weeks, skin becomes firmer, tighter, and more elastic.
Think of Profhilo as “liquid scaffolding” — it doesn’t fill, it rebuilds.
Who Is Profhilo For?
✅ Right candidates:
● 30–65 years old with early or moderate skin laxity.
● Fine lines, dullness, crepey skin.
● Post-weight loss or post-pregnancy skin quality loss.
❌ Not ideal candidates:
● Severe sagging → better with surgery/energy-based devices.
● Volume loss → fillers or fat grafting are better options.
● Active infection, autoimmune skin disease, pregnancy/breastfeeding.
● 30–65 years old with early or moderate skin laxity.
● Fine lines, dullness, crepey skin.
● Post-weight loss or post-pregnancy skin quality loss.
❌ Not ideal candidates:
● Severe sagging → better with surgery/energy-based devices.
● Volume loss → fillers or fat grafting are better options.
● Active infection, autoimmune skin disease, pregnancy/breastfeeding.
Clinical Evidence
● Bianchi et al, 2019 (Aesthet Surg J) → Profhilo improved hydration, elasticity, and dermal thickness at 8 weeks.
● Dall’Oglio et al, 2016 (Clin Cosmet Invest Dermatol) → significant increase in collagen and elastin fibres, reduction of fine lines.
● Profhilo clinical data → >80% patient-reported satisfaction for skin quality.
● Dall’Oglio et al, 2016 (Clin Cosmet Invest Dermatol) → significant increase in collagen and elastin fibres, reduction of fine lines.
● Profhilo clinical data → >80% patient-reported satisfaction for skin quality.
FAQs
How many sessions do I need?
Usually 2 sessions, 4 weeks apart. Maintenance every 6–9 months.
Does Profhilo change face shape?
No. It’s not a filler. It improves skin quality, not volume.
Is it painful?
Minimal discomfort. Uses BAP technique (5 points per side).
Downtime?
Mild swelling/redness 24–48 hrs. No long downtime.
Treatment Areas
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Profhilo Face £325
Restores firmness and hydration to cheeks, jawline, temples, and mid-face.
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Profhilo Neck £325
Tightens crepey, sagging skin, improves neck lines.
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Profhilo Body (Per Area) £550
Especially effective for arms, abdomen, hands, and above-knee laxity.
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Profhilo Two Areas (Face + Neck) £450
For combined rejuvenation.
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Profhilo Three Areas (Face + Neck + Décolleté) £650
Full upper-body bio-remodelling.