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Cross-Linked Hyaluronic Acid Skin Booster at Dr Hans Clinics

Hydromax (Stylage® HydroMax Skin3 Complex) is a cross-linked hyaluronic acid skin booster designed to improve skin hydration, elasticity, fine lines, and overall skin quality without adding volume.

At Dr Hans Clinics, we use Hydromax for patients who want:

  • Smoother skin
  • Better hydration
  • Reduced crepiness
  • Subtle firming
  • A healthier, denser skin appearance
  • Natural results, not filler look
This is not a volumising filler. It is a skin quality treatment.

What Is Hydromax?

Hydromax is a 12.5 mg/ml hyaluronic acid injectable gel composed of :
● Cross-linked hyaluronic acid
● Free high molecular weight hyaluronic acid
● Sorbitol-enriched phosphate buffer

This combination is referred to as the Skin3 Complex
Unlike purely non-cross-linked skin boosters, Hydromax contains cross-linked HA, which increases tissue persistence and structural support.
It is injected into the deep dermis or dermo-hypodermal junction depending on technique.

How Does Hydromax Work?

Hydromax is marketed as targeting three skin layers:

● Epidermis
● Dermo-epidermal junction (DEJ)
● Dermis

Preclinical laboratory data on reconstructed aged skin models demonstrated increased expression of:

● Ceramides
● Aquaporin-3
● Dermis
● Filaggrin
● Collagen type I
● Emilin-1
● Collagen type XVII
● Ki67

In simple terms, the laboratory model showed markers linked to:

● Barrier function
● Water transport
● Epidermal renewal
● Collagen structure
● Elastic fibre support

Important : These are preclinical lab findings, not large independent randomised human trials. We explain this clearly to patients.

What Does That Mean Clinically?

In small clinical and workshop-based data (2024):
● Cheek wrinkles reduced after 2 sessions
● Moisturisation significantly increased
● 80 – 90% patient satisfaction
● GAIS improvement reported by evaluators and subjects

Reported durability : 6 – 9 months depending on skin and lifestyle

Realistically?

● You will not look different.
● You will look better.
● Skin appears smoother, fresher, more hydrated.
Subtle, not dramatic.

What Areas Can Be Treated?

● Cheeks
● Lower face
● Neck
● Décolleté
● Hands
● Perioral lines
● Accordion lines

At Dr Hans Clinics, we individualise the approach depending on:

● Skin thickness
● Age
● Degree of laxity
● Fine line pattern
● Treatment goals

Subtle, not dramatic.

Who Is a Good Candidate?

Hydromax is suitable for :
● Early skin laxity
● Crepey texture
● Dull skin
● Mild fine lines
● Dehydrated skin
● Post-weight-loss skin thinning
● Patients wanting improvement without filler volume

It is especially useful in patients who :

Hydromax is suitable for :
● Do not want facial volume
● Want natural improvement
● Have previously had filler but now want refinement

Who Is NOT Suitable?

Hydromax is not ideal if :
● You have significant skin laxity requiring structural lift
● You expect dramatic tightening
● You need volume restoration
● You want deep wrinkle correction
● You want a “one session miracle”

Honest view :

● Profhilo spreads widely but lacks cross-linking, so durability may be shorter.
● Volite is more intradermal hydration focused.
● Vital requires 3 sessions.
● Hydromax sits between hydration and dermal support.


No product is universally “better”.

It depends on indication.

Why We Use Hydromax at Dr Hans Clinics
We use it when:
Skin needs density without filler
• Fine crepiness is present
• Barrier dysfunction is obvious
• You want natural, subtle improvement

Evidence & Expectations

Let’s be very clear.
Evidence includes :
● Preclinical reconstructed skin model data
● Small clinical and workshop-based patient cohorts.
● Practitioner surveys.


There are currently no large independent RCTs comparing Hydromax head-to-head in high-quality trials.

Results vary

Improvements are:
● Subtle
● Progressive
● Natural


If you want dramatic lifting, this is not it.

Safety

Hydromax is :
• CE marked Class III medical device
• Based on hyaluronic acid, a naturally occurring molecule
• Reversible with hyaluronidase

Common side effects :
• Redness
• Swelling
• Bruising
• Tenderness

Rare risks (as with all injectables) :
• Vascular occlusion
• Infection
• Nodules

Downtime: usually 24 – 48 hours mild swelling

Safety

Hydromax is Common side effects Rare risks (as with all injectables)
CE marked Class III medical device
Redness
Vascular occlusion
Based on hyaluronic acid, a naturally occurring molecule
Swelling
Infection
Reversible with hyaluronidase
Bruising & Tenderness
Nodules

Downtime: usually 24 – 48 hours mild swelling

Treatment Protocol at Dr Hans Clinics

Standard protocol based on manufacturer guidance :
• 2 sessions
• 4 weeks apart
• Maintenance every 6 months

Typical dose:
• 1 ml per side of face per session
• Neck: 1 – 2 ml
• Hands: 1 – 3 ml total

Techniques:
• Cannula fanning
• Linear threading
• Multipoint microinjections

Depth : Deep dermis or dermo-hypodermal junction .

Treatment Protocol at Dr Hans Clinics

Standard protocol based on
manufacturer guidance
Typical dose Techniques
2 sessions
1 ml per side of face per session
Cannula fanning
4 weeks apart
Neck: 1–2 ml
Linear threading
Maintenance every 6 months
Hands: 1–3 ml total
Multipoint microinjections

Depth : Deep dermis or dermo-hypodermal junction 

Hydromax vs Profhilo vs Other Skin Boosters

Below is a simplified, honest comparison.
Feature Hydromax Profhilo Volite Restylane Vital
2 sessions
HA Type
Cross-linked + free HA
Non-cross-linke d hybrid HA
Cross-linked HA
Concentration
12.5 mg/ml
32 mg/ml
12 mg/ml
20 mg/ml
Longevity
6 – 9 months
~4 – 6 months
Up to 9 months
Up to 12 months after 3 sessions
Sessions
2 Sessions
2 Sessions
Often 1
3 Sessions
Injection Depth
Deep dermis / junction
Superficial dermis / subcut
Intradermal
Dermal
Main Focus
Barrier + renewal + dermal density
Bio-remodelling
Hydration + fine lines
Hydration + smoothness
Volume Effect
No volumisation
No volumisation
Minimal
Slight structural feel

Depth : Deep dermis or dermo-hypodermal junction 

FAQs

When will I see results?

Hydration improvement can be visible within 2 – 3 weeks. Best results are typically after the second session

On average 6 – 9 months
Longevity depends on:
• Smoking
• Sun exposure
• Metabolism
• Skin quality baseline

No. It is not a volumising filler.

Mild discomfort.
Topical anaesthetic is used.
Cannula techniques reduce trauma.

Yes, but not usually necessary. We choose one based on your skin indication.
Not first choice. Under-eyes require careful assessment and often different products.
Yes, particularly mild to moderate crepiness.

There is no universal “better”.

    1. Hydromax may offer:
      • Slightly more structural persistence
      • Slightly longer duration
      • More dermal support
    2. Profhilo may offer:
      • Greater diffusion
      • Simpler BAP technique

Choice depends on skin.

Not in the same category as Sculptra or Radiesse. It is HA-based dermal optimisation.

Hydromax London - Book a Consultation

If you are looking for:

  • Natural skin improvement
  • No filler face
  • Evidence-based approach
  • Honest discussion about realistic outcomes

Book a consultation at Dr Hans Clinics London.
We treat the problem, not sell the product.

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