EVIDENCE & SAFETY
● Studies support HA filler as a safe and effective approach for midface fold correction when combined with structural restoration techniques (Aesth Surg J 2020; J Cosmet Dermatol 2021).
● Common effects include mild swelling or tenderness for 24 – 48 hours.
● Rare complications (vascular occlusion, nodules) are mitigated through aspiration, slow injection, and hyaluronidase preparedness.
● Contraindications: infection, pregnancy, recent dental work, or prior filler migration in the region.